Open Access DOI:10.23937/2377-3634/1410011
Assessment of Learning Guides Improvement in Diabetes Education Program: A QI Initiative for Type I Diabetes Mellitus in Children and Adolescents
Manmohan K. Kamboj, Kathryn J. Stephens, Richard J. Brilli, Heather L. Yardley, Jeff Lewis, Richard E. McClead, Jr. and David R. Repaske
Article Type: Research Article | First Published: November 17, 2014
Aims: To develop objective assessment tools to evaluate proficiency of well-day (WD) and sick-day (SD) diabetes knowledge and management skills in families of pediatric type 1 diabetes patients and to utilize this information to modify our diabetes education (DE) program to improve learning of the desired knowledge and skills.
Methods: Vignette-based assessment quizzes were developed to evaluate WD and SD diabetes knowledge and management skills. Vignettes assessed basic knowledge and skills i...
Open Access DOI:10.23937/2377-3634/1410010
Type 2 Diabetes and Lifestyle- A Prospective Population-Based Cohort Study among Rural Men
Anders Thelin and Sara Holmberg
Article Type: Research Article | First Published: November 16, 2014
The risk of type 2 diabetes (T2D) is related to lifestyle but less is known about how lifestyle factors interact and how they impact the risk when combined. This study was performed to analyze how lifestyle factors relate to the cumulative incidence of T2D in a Swedish rural population. Outcomes were generated from national registers and from two surveys. Two hundred sixty men (11%) with diabetes were found in the registers, and 193 men with T2D were identified in the surveyed population (9.8%)....
Open Access DOI:10.23937/2377-3634/1410009
Role of Infections in Children with Diabetic Ketoacidosis- A Study from South India
Poovazhagi Varadarajan and Saradha suresh
Article Type: Original Article | First Published: November 06, 2014
Cerebral edema is the commonest cause of mortality in DKA worldwide. Infections are known to precipitate new onset DKA, they also adversely affect the outcome of DKA in children from developing countries. Infections are major contributory factors for DKA in children with established diabetes mellitus (DM) along with poor compliance to therapy. This study among 118 episodes of DKA from a pediatric tertiary care Institute has identifid infections as a signifiant risk factor for severe metabolic de...
Open Access DOI:10.23937/2377-3634/1410008
The Role of Netrin-1 in Diabetic Retinopathy: A Promising Therapeutic Strategy
Wenyi Wu and Luosheng Tang
Article Type: Review Article | First Published: November 06, 2014
Netrin-1 which belongs to axon guidance cue is necessary for neural and vascular development. It involves in regulating axon guidance for attraction or repulsion and it has a dual function in endothelial tip cell migration during angiogenesis. Many evidences have proved that netrin-1 plays an important role in angiogenesis, cancer progression and inflmmation disease. Here we provide a comprehensive review on the role of netrin-1 in retinal and angiogenesis developments. What's more, some associa...
Open Access DOI:10.23937/2377-3634/1410007
Does GABA Metabolism Play any Specific Role in the Stimulation of Insulin Secretion in Β-Cells?
J. Pizarro-Delgado and J. Tamarit-Rodriguez
Article Type: Review Article | First Published: November 05, 2014
It was recognized quite a few years ago that islet GABA metabolism might be implicated in the stimulation of insulin secretion by glucose. Since then, some studies have been addressed to investigate how GABA release by β-cells might exert a negative autocrine control of glucose-stimulated insulin secretion and a parallel paracrine inhibition of glucagon release trough the activation of GABAB and GABA A receptors, respectively. More recently, it has been shown that some nutrient secretagogue...
