Open Access DOI:10.23937/2377-3634/1410046
Why so Fat ?
Franco Contaldo, Maurizio Marra, Lidia Santarpia and Fabrizio Pasanisi
Article Type: Hypothesis | First Published: October 28, 2015
We selected, from our database of obese outpatients, 90 young severely obese subjects (60 females, 30 males) in a stable body weight since at least 6 months, age range 20 - 30 years, who underwent measurements of resting energy expenditure (REE) by indirect calorimetry (VMax Sensor Medics) and body composition was evaluated by bioelectrical impedance (BIA). Bio impedance analysis (BIA) was performed at 50 kHz (Human Im plus II, DS Medica) in standard conditions....
Open Access DOI:10.23937/2377-3634/1410045
Perceptions of a Culturally Tailored Adapted Program to Prevent Type 2 Diabetes
Angela Cooper Brathwaite and Manon Lemonde
Article Type: Research Article | First Published: October 19, 2015
Objective: To explore African and Caribbean immigrants' perceptions of a culturally tailored intervention to prevent type 2 diabetes. Methods: Using a purposive sampling scheme, 29 participants (26 women and 3 men, mean age 48 years and average length of residency of 22 years in Canada) participated in this study. The researchers used in-depth focus groups and individual surveys to collect qualitative data from participants. Following these interviews, participants individually reviewed the inte...
Open Access DOI:10.23937/2377-3634/1410044
The Safety, Efficacy and Treatment Satisfaction Comparison of Unchanged Premixed Insulin Regimen Plus Sitagliptin with Switch from the Premixed Insulin to Once-Daily Basal Insulin Plus Sitagliptin in Patients with Inadequately Controlled Type 2 Diabetes with Twice-Daily Premixed Insulin
Kanako Ono, Akinobu Nakamura, Junko Kawaguchi, Masahiro Takihata, Yuichiro Inoue, Jun Shirakawa, Akiko Kameda, Yu Togashi, Tsutomu Hayashi, Takayuki Furuki, Shun Ito, Tatsuro Takano, Satsuki Kawasaki, Hiroshi Takeda, Tetsuji Kaneko, Mari Kimura, Shunsaku Mizushima and Yasuo Terauchi
Article Type: Original Article | First Published: September 30, 2015
Background: While adding sitagliptin to insulin therapy for Type 2 Diabetes Mellitus (T2DM) showing poor response to therapy with premixed insulin alone, we compared the efficacy and safety and satisfaction from continuing treatment with the premixed insulin versus switching of the premixed insulin to basal insulin therapy. Methods: The study was an open-label, randomized controlled trial conducted at 7 institutions in Japan. The study participants were randomly assigned to one of two treatment ...
Open Access DOI:10.23937/2377-3634/1410042
Renal Denervation, Blood Pressure and Metabolic Disease: Not a Simple Solution
Cathryn M. Kolka
Article Type: Commentary | First Published: September 01, 2015
Diabetes, obesity, cardiovascular disease and hypertension are frequently grouped together as the 'metabolic syndrome'. The prevalence of these diseases is increasing in the United States and worldwide. In recent years, overactivity of the sympathetic nervous system has been linked to obesity, hypertension, and cardiovascular disease. Promising initial research investigated the role of the sympathetic nervous system in hypertension: renal denervation using catheter-based radiofrequency ablation ...
