International Journal of

Diabetes and Clinical ResearchISSN: 2377-3634

Archive

 Open Access DOI:10.23937/2377-3634/1410062

The Impact of Energy Drink Consumption on Vascular Endothelial Function

R Matthew Brothers

Article Type: Research Article | First Published: June 07, 2016

Vascular endothelial dysfunction contributes to a variety of cardiovascular and metabolic diseases. Despite anecdotal reports of adverse cardiovascular and hemodynamic effects of energy drink consumption there has been very little scientific research conducted on this important topic. Furthermore, the limited research available has not yielded consistent results. This study tested the hypothesis that consumption of a commercially available energy drink would have no effect on endothelial functio...

 Open Access DOI:10.23937/2377-3634/1410061

Ethanolic Extract of Bauhinia forficata: Metabolic Effects in Diabetic and Normoglycemic Rats

Liana de Oliveira Gomes, Francislaine Aparecida dos Reis Livero, Aline Maria Stolf, Carlos Eduardo Alves de Souza, Michele Pontes Werneck, Cristiane Vizioli de Castro Ghizoni, Maria Helena Verdan, Jose Ederaldo Queiroz Telles, Rosangela Locatelli Dittrich, Maria Elida Alves Stefanello, Jurandir Fernando Comar and Alexandra Acco

Article Type: Original Article | First Published: June 06, 2016

Diabetes is a group of metabolic diseases characterized by hyperglycemia and associated complications, such as dysfunction and failure of the eyes, kidneys, nerves, brain, heart, and blood vessels. Diabetes may result from defects in secretion and/or insulin action involving specific pathogenic processes, including destruction of pancreatic beta cells, insulin resistance, and insulin secretion disorders. The estimated prevalence of diabetes nowadays is about 150 million people worldwide, and thi...

 Open Access DOI:10.23937/2377-3634/1410060

Evaluation of a Standardized Inpatient Insulin Therapy Based on Electronic Insulin Dose Calculation - A before after Cohort Proof of Concept Study

Rahel Nussbaumer, Philipp Schuetz, Beat Mueller, Robert Thomann and Anne Katrin Borm

Article Type: Original Research Article | First Published: May 31, 2016

Background: Diabetes is a common comorbidity in hospitalized patients. The necessity of blood glucose control in those patients with low variability and avoidance of hypoglycemic episodes is well-known. Yet, there is still only marginal literature about the optimal therapy of hyperglycemia in non critically ill hospitalized patients using tools of modern electronic patients charts. Objectives:The present study aimed to investigate the feasibility, the safety and efficiency of a standardized inpa...

 Open Access DOI:10.23937/2377-3634/1410059

Exogenous Phosphatidyl-Serine and -Ethanolamine Supports Anti-Proliferative and Chemoresistance Properties of ATAD3B and Induces S100B Recruitment at Mitochondria

Denis Rousseau

Article Type: Research Article | First Published: May 27, 2016

ATAD3 protein is a S100B- and PKC-regulated mitochondrial ATPase which is vital for mitochondrial biogenesis and early development. Even if suspected today to contribute in a lipid rafts transfer system, from endoplasmic reticulum to mitochondria, the precise function of ATAD3 is still unknown. However, ATAD3 has been previously shown to exhibits in vitro anti-proliferative and chemo resistant properties and to be a positive marker of different tumor subtypes, of tumor progression and of poor su...

 Open Access DOI:10.23937/2377-3634/1410058

Diabetes in Rural Rwanda: High Retention and Positive Outcomes after 24 Months of Follow-up in the Setting of Chronic Care Integration

Neo Tapela, Hamissy Habineza, Sarah Anoke, Emmanuel Harerimana, Francis Mutabazi, Bethany L. Hedt-Gauthier, Symaque Dusabeyezu, Pie X F. Uwiragiye, Cadet Mutumbira, Gedeon Ngoga, Deogratias Ndagijimana, Emmanuel Rusingiza, Gene Bukhman and Charlotte Bavuma

Article Type: Research Article | First Published: May 20, 2016

Aims:This study describes the baseline characteristics and 24 month outcomes of diabetic patients managed in an integrated chronic care program at public facilities in rural Rwanda. Methods:Retrospective review of routine electronic medical records of patients treated for diabetes between October 1, 2006 and September 30, 2014 was conducted. Baseline demographic and clinical characteristics are described. Outcomes of HbA1c values, loss to follow-up and death are reported....

 Open Access DOI:10.23937/2377-3634/1410057

Continuous Insulin Releasing and Blood Sugar Monitoring via Dental Implant Supported Semi-Implanted Device

Yu-Jung Li

Article Type: Research Article | First Published: May 17, 2016

As life expectancy prolonged currently, geriatrics become important and therefore it is urgent to improve the life quality throughout the chronic and critical diseases among the elderly above sixty-fifth years old. On the other hand, diabetes mellitus (DM) is the most famous chronic and metabolic disease which may lead to many cardiac, renal and infectious complications. Therefore regular blood sugar control is extremely important in diabetic management to avoid further complications. However, t...

 Open Access DOI:10.23937/2377-3634/1410056

The Effects of a One-week Short Intensive Insulin Intervention on Insulin Sensitivity in Patients with Poorly Controlled Type 2 Diabetes

Jean-Claude Katte, Eugene Sobngwi, Vicky Kamwa, Mesmin Y Dehayem, Jean-Louis Nguewa, Andre-Pascal Kengne and Jean Claude Mbanya

Article Type: Research Article | First Published: May 12, 2016

A 3-4 week of intensive insulin intervention corrects hyperglycemia, improves insulin secretion, glycemic control, and insulin sensitivity in people with type 2 diabetes mellitus. We assessed the effect of a shorter course of intensive insulin therapy on insulin sensitivity in people with T2DM. Fifteen poorly controlled subjects with severe hyperglycemia were hospitalized and treated with intensive insulin therapy for 7 days. The short insulin tolerance test was performed before and after the in...

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