Open Access DOI:10.23937/2474-3658/1510017
Lemierre's Syndrome without Internal Jugular Vein Thrombophlebitis: A Diagnostic Conundrum
Gbolahan O Ogunbayo, Josephine Adunse, Odunayo Olorunfemi and Nashwa Abdulsalam
Article Type: Case Report | First Published: August 16, 2016
A previously healthy 23-year-old male presented with fever and shortness of breath. His illness initially started six days before presentation with a sore throat. Two days later he developed fevers with associated chills, rigors, and night sweats. He also complained of myalgias, non-productive cough, a right-sided chest pain, and shortness of breath on exertion, as well as nausea, vomiting, abdominal pain, and diarrhea. His symptoms continued to worsen until he became dyspneic at rest and was br...
Open Access DOI:10.23937/2474-3658/1510015
Dengue Fever: Historical Perspective and the Global Response
Tyler Warkentien and Rebecca Pavlicek
Article Type: Review Article | First Published: July 02, 2016
Dengue fever remains an important mosquito-borne viral illness resulting in substantial human and economic costs. Despite rising incidence rates in recent decades, there is cause for hope, particularly in light of recent advancements in dengue vaccine and vector control research. This article reviews past dengue control efforts and discusses current and future strategies for dengue control....
Open Access DOI:10.23937/2474-3658/1510014
Essential Transition Metal Ion Complexation as a Strategy to Improve the Antimicrobial Activity of Organic Drugs
Graciela Borthagaray, Melina Mondelli and Maria H Torre
Article Type: Review Article | First Published: May 02, 2016
In order to maintain the capacity to treat infections it is necessary to adopt strategies for the development of new drugs. The use of metal ions in medicine for their antimicrobial effects was prevalent for many years before the advent of antibiotics. During the second half of the twentieth century, active metal complexes with different chemical, physicochemical and biochemical properties than the constituents reborn by the threat posed by microbial multidrug resistance....
Open Access DOI:10.23937/2474-3658/1510013
Tuberculosis Control in Jiangsu Province, China
Li Yan, Zhu Limei, Cheng Chen, Lu Wei, Booker G.W, Yu Hao and Polyak S.W
Article Type: Review Article | First Published: May 02, 2016
Tuberculosis (TB) has been a major health problem for thousands of years. It took almost 200 years after the discovery of the disease in early 1689 to identify the causative pathogen, namely Mycobacterium tuberculosis by Robert Koch who was awarded a Nobel Prize in physiology or medicine in 1905 for his work in this area. Currently, TB is a global pandemic that outranks HIV-AIDS and malaria as the leading cause of death by infectious disease. In 1993 the World Health Organization declared TB a g...
