Open Access DOI:10.23937/2474-3658/1510119
Past, Present and Future of Pandemics (COVID-19)
Mzee Said Abdulrahman Salim and Muslimat Kehinde Adebisi
Article Type: Review Article | First Published: April 30, 2020
From herpes and legionnaires' disease in the 1970s to AIDS, Ebola, the severe acute and respiratory syndrome (SARS), contagious diseases continue to threaten and disrupt human societies. The end of last year (2019) doctors in Hubei province encountered patients with flu-like symptoms that are similar in characteristics to SARs having consistent aetiologies unfamiliar to them but with a possible link to their prior knowledge. A virus outbreak which has a genomic sequence similar to that of β vir...
Open Access DOI:10.23937/2474-3658/1510120
Further Evidence of a Possible Correlation between the Severity of Covid-19 and BCG Immunization
Serge Dolgikh
Article Type: Original Article | First Published: April 30, 2020
In this work we observe a number of cases supporting the possible correlation between the administration of BCG tuberculosis vaccine and the severity of Covid-19 effects in the population proposed in the earlier works. Based on the early preliminary analysis of the publicly available data we propose a number of arguments and observations providing further support for the correlation hypothesis and make an observation that the effectiveness of the protection effect of BCG immunization, if confirm...
Open Access DOI:10.23937/2474-3658/1510117
Ozone Autohemotherapy: Possible Mechanisms of Anti-Viral Action and Anti Oxidative
Bilal Mohamad Ali Obeid, MD, MBA, PHD
Article Type: Review Article | First Published: April 29, 2020
While ozone is the trigger, several blood components such as erythrocytes, lymphocytes, monocytes, polymorphonuclear leukocytes, platelets, and plasma components act as substrates and are responsible for setting in motion a number of biological effects that, directly or indirectly, are responsible for the clinical improvement observed after the autohaemotherapeutic treatment in chronic viral diseases...
Open Access DOI:10.23937/2474-3658/1510118
Strategies of the World Health Organization in the Covid 19 Outbreak
Emel Yürük Bal, (RN) MSc and Şenay Çetinkaya, PhD
Article Type: Commentary | First Published: April 30, 2020
Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Coronaviruses are single-chain, positive-polar, enveloped RNA viruses. Over the past 2 weeks, the coronavirus disease 2019 (COVID-19) pandemic has marched relentlessly westward. On March 13, WHO said that Europe was now the centre of the pandemic. A few days later, deaths in Italy surpassed those in China. Iran and Spain had also reported over 1000 deaths as of March 23, and many other European coun...
Open Access DOI:10.23937/2474-3658/1510115
Hepatitis B Envelope Antigen in Adult Carriers of Chronic Hepatitis B Surface Antigen in a Tertiary Health Facility in North East Nigeria: 2000 - 2015
Isaac Warnow Elon, Jalo Iliya, Alkali Yaya, Ajani Ayomikun, Abubakar Joshua Difa, Oyeniyi C, Aremu John and Danlami Halilu
Article Type: Original Article | First Published: April 09, 2020
Hepatitis B infection continues to be a serious global health problem with about 2 billion people infected worldwide, many of these in sub-Saharan Africa. Records of Hepatitis B surface and envelope antigen test results in adults attending the outpatient units and/ or admitted in Federal Teaching Hospital, Gombe between May 2000 and May 2015 were retrieved and analyzed. Hepatitis B surface antigen was tested for in 22,862 adults and children; 20375 (89.1%) were adults and 2487 (10.9%) were child...
Open Access DOI:10.23937/2474-3658/1510116
COVID-19 Threat to Major Global Urban Centers
Jean-dAmour K Twibanire
Article Type: Original Article | First Published: April 22, 2020
The world is facing an unprecedented test by an enemy, a novel and deadly enemy, the COVID-19 pandemic. As COVID-19 continues to spread all around the world, social, political and serious economic consequences await this planet. After the introduction and a brief epidemiological summary, this article discusses the threat that is COVID-19 to major global urban centers. The impact of COVID-19 across the globe is particularly inimitable and more so in major global urban centers for several reasons ...
Open Access DOI:10.23937/2474-3658/1510114
MMR Vaccine Adverse Drug Reactions Reports in the CDC WONDER System, 1989-2019
Guillermo Rodriguez-Nava, MD, Maria Adriana Yanez-Bello, MD and Danieal Patricia Trelles-Garcia, MD
Article Type: Brief Report | First Published: March 14, 2020
We retrieved data from the Vaccine Adverse Event Reporting System (VAERS) database, a national post-licensure vaccine safety surveillance system, through the CDC WONDER interface for reports of children aged 12 months to 6 years vaccinated with the MMR vaccine in the U.S. between January 1, 1989 and January 1, 2019. Specific ADRs evaluated in this analysis included anaphylaxis, febrile seizures, encephalitis, and orchitis. Disproportionate reporting of ADRs was assessed using proportional report...
Open Access DOI:10.23937/2474-3658/1510113
A Plausible
Robert Jay Rowen, MD and Howard Robins, DPM
Article Type: Commentary | First Published: March 06, 2020
Many viruses require reduced sulfhydryl groups for cell fusion and entry. Corona viruses, including SARS-CoV-2 (the cause of the condition now named coronavirus disease 2019 or COVID-19), are rich in cysteine, which residues must be intact for viral activity. Sulfhydryl groups are vulnerable to oxidation. Ozone therapy, a very inexpensive and safe modality may safely exploit this critical vulnerability in many viruses, inclusive of SARS-CoV-2. Mainstream medicine has little in its arsenal for vi...
Open Access DOI:10.23937/2474-3658/1510112
Deferring Antibiotic Prescribing in Nursing Home Residents with Asymptomatic Bacteriuria: A Pilot Educational Intervention
Emilie Kennedy, DNP, CRNP, FNP-C
Article Type: Clinical Research Article | First Published: March 04, 2020
Unnecessary antibiotic use in nursing home patients leads to negative outcomes including the emergence of multi-drug-resistant bacteria, adverse drug events, polypharmacy and higher health care costs. The purpose of this study was to develop and assess the effects of a pilot clinical staff educational intervention on best practices for the management of asymptomatic bacteriuria (ASB) in nursing home residents. A multi-faceted educational intervention program on ASB was provided to Emergency Depa...
