Open Access DOI:10.23937/2474-3658/1510243
The COVID-19
Luiz Gonzaga Francisco de Assis Barros D’Elia Zanella, MD
Article Type: Original Research | First Published: January 13, 2022
There is a significant imbalance in the generation of NAD/NADH+ (niacin), which affects chemical reactions in the intracellular environment in COVID-19 and yellow fever. From tryptophan and its metabolic pathways and oxidative stress, the process of understanding SARSCoV- 2 infection becomes more concrete, as the infection seems to interfere in these metabolic pathways, in addition to the paradoxical role of kynurenine that causes inflammation by blocking the BH4 pathway. Understanding metabolic...
Open Access DOI:10.23937/2474-3658/1510246
Cholera Scourge in Nigeria: Promoting Environmental Sanitation Practice to Achieving Good Health for All
Olajide Mariam Olaitan, Tajudeen Kaosarat Oluwatobi, Popoola Victor Oluwaseun, Onyeanusi Sandra Adaobi, Makinde Abubakar Abiodun, Oladapo Rasaq Kayode, Onyinyechi Patience Obidiro, Oyetola Afeez Babatunde, Adekunle Olajide and Akinrinde Barakat
Article Type: Commentary | First Published: January 31, 2022
The present surge in cholera cases in Nigeria especially among the vulnerable is quite worrisome and alarming. Several factors account for the prevalence of cholera in Nigeria, which includes but is not limited to poor living conditions, lack of potable water, sanitation, and hygiene (WASH) services. Interestingly, Environmental sanitation has been identified as integral in achieving a healthy environment. It involved controlling all the factors in man’s physical environment which may cause ha...
Open Access DOI:10.23937/2474-3658/1510245
Persistence Viral Shedding of SARS-CoV-2 in Feces and Potential Transmission
Mauro MV, Greco S, Vitiritti M, Elia N, Mastroianni A and Greco F
Article Type: Original Article | First Published: January 30, 2022
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths worldwide. Despite the recent availability of vaccines, with the ongoing and rapid spread of SARS-CoV-2 worldwide, laboratory testing remains the cornerstone of public health containment and mitigation strategies. Also, although not used routinely in many laboratories, detecting SARS-CoV-2 RNA from stool is possible in the pres...
Open Access DOI:10.23937/2474-3658/1510244
COVID-19: SARS-CoV-2 Seroprevalence in a Blood Bank in Southern Brazil
Maria Augusta Bogo, Djulia Adriani Frainer, Luisa Pisacane, Paulo Henrique Condeixa de França and Luiz Henrique Melo
Article Type: Original Article | First Published: January 14, 2022
To determine the seroprevalence of antibodies to SARS-CoV-2 in asymptomatic individuals in a blood bank in southern Brazil. 1015 serological analyses were performed between November 2020 and March 2021 in Joinville, Brazil, to detect IgG and IgM antibodies against SARSCoV- 2, and the results were correlated with the participants' age, gender, city and neighborhood. The seroprevalence of total antibodies was 40.4%, with reagent IgM detected in 9.4% of cases, IgG in 18.5% and both immunoglobulins ...
