Open Access DOI:10.23937/2469-5726/1510049
Rheumatic Disease Frequency in Hospitilized Acute Stroke Patients
Nihal Ozaras, M Serdar Sag, M Akif Sariyildiz and Sule Deveci
Article Type: Letter to the Editor | First Published: February 21, 2017
Rheumatic diseases (RD) have increased risk for stroke. We examined the records of acute stroke patients for concomitant diseases. Two of 178 patients had gout, no other RD was detected. Considering the result of our study and current evidence in the literature, we suggest that patients with gout should be monitored closely for the risk of stroke and the clinician should be aware of higher risk of stroke in these patients....
Open Access DOI:10.23937/2469-5726/1510048
SLE - Update Ethiopathogenesis Leading to Biological Therapy
J Rovensky, S Blazickova and I Stiborova
Article Type: Review Article | First Published: February 21, 2017
Systemic lupus erythematosus is a chronic, autoimmune disorder which may have even fatal consequences, particularly if it affects vital organs of the human body. It is typically manifested by inflammation of various organ systems. The course of the disease includes sporadic flare-ups, or relapses, which may lead to irreversible damage of the organs. The focus is on the suppression of clinical symptoms, inhibition of the formation of autoantibodies induce remission, preventing relapse and irrever...
Open Access DOI:10.23937/2469-5726/1510047
Glucocorticoid-Induced Leucine Zipper (Gilz) in Rheumatoid Arthritis: Relationship with Disease Activity and Steroid Use
Laura E Eades, Angeline S Thiagarajah, Sarah A Jones, Huapeng Fan, Anastasios Nalpantidis, Eric F Morand and Michelle Leech
Article Type: Research Article | First Published: February 21, 2017
Clinical data was obtained from RA patients and medical records. Three control cohorts were also recruited, including 23 healthy controls, 25 patients with fibromyalgia and 44 patients with depression. Blood was taken from each participant. Following isolation of peripheral blood mononuclear cells (PBMC) from whole blood, RNA was extracted. Reverse transcription polymerase chain reaction (RT PCR) and quantitative real time PCR (qPCR) were performed to quantify GILZ expression....
Open Access DOI:10.23937/2469-5726/1510046
Scleroderma Renal Crisis
Gioacchino Li Cavoli, Luisa Bono, Calogera Tortorici, Carlo Giammarresi, Tancredi Vincenzo Li Cavoli and Ugo Rotolo
Article Type: Case Report | First Published: February 14, 2017
Scleroderma or Systemic sclerosis is a vascular and fibrotic disease with organ-based complications and high mortality and morbidity. Renal involvement can be quite varied and scleroderma renal crisis is the most severe manifestation. We report our experience. In February 2016 a 52-year-old male was admitted to hospital with pulmonary oedema and severe arterial hypertension (240/120 mmHg)....
Open Access DOI:10.23937/2469-5726/1510044
Is There a Correlation Between DAS28/RADAI in a Cohort of Rheumatoid Arthritis Patients Treated with Biological Therapy
Hèctor Corominas, Silvia García-Diaz, Salvador Campos, Silvia Sánchez-Serrano, Silvia Iniesta, Isabel Padró, Lucinda Sanchez-Eslava, Elena Fernández-Casado, Montse Sesma, Cristina Saura, Mari Carmen Rodríguez, Maria Rusiñol and Montse Jordana
Article Type: Research Article | First Published: January 31, 2017
Rheumatoid arthritis (RA) is a chronic inflammatory heterogeneous disease presenting with acute flares, showing a prevalence of 0.5% in Spanish population according to the study EPISER and an annual incidence of 8.3 cases per 100,000 population, and that in the absence of optimal and individualized treatment causes a long-term severe disability....
