Table 1: Parameter definitions used during analysis.
Item |
Definition |
Buruli ulcer case |
• Lesions were clinically assessed to be consistent with Buruli ulcer lesions by experts. • Lesions positive for M. ulcerans by PCR and positive for mycolactone detection by f-TLC from a swab or fine needle aspirates (FNA). |
Surgical definitions |
• Major surgery: Closure of an excised lesion using a split skin or full-thickness skin graft or vascularized tissue flap. |
Long-course Antibiotics |
• Duration of antibiotics 8 weeks (56 days) |
Treatment success |
• Healing of the entire lesion without recurrence after the antibiotic treatment course had been completed. |
Treatment outcomes |
• Antibiotic treatment completed. • Antibiotic treatment not completed. • Healed without surgery. • Healed with surgery. • Healed without limitation of movement to any joint. • Healed with limitation of movement to any joint. |