Table 3: Syndromic congenital anosmia and Kallmann syndrome.

Patients N = 22 Gender Age Genetic diagnosis UPSIT STOE MRI Pituitary gland Olfactory central structures OB evaluation SR OB evaluation SM
1 F 34 ND 3 c D N ND 0 0
2 M 18 KAL1 3 c D N ND 2 2
3 F 60 ND ND c ND ND ND ND ND
4 M 16 ND ND c D N ND 0 0
5 F 36 ND ND c D N ND 0 0
6 M 18 ND ND c D N ND 2 2
7 F 32 ND 3 c ND ND ND ND ND
8 F 18 ND ND c D N aN 2 2
9 M 16 AWAITED 3 c D N aN 2 2
10 F 21 FGFR1/PROKR2 3 ND D N ND 2 2
11 F 9 KAL1 3 c D N ND 2 2
12 F 28 ND ND c ND ND ND ND ND
13 M 14 ND ND c D N aN 1 1
14 F 16 ND ND c D N ND 2 2
15 M 9 KAL1 3 c D N aN 2 2
16 M 21 KAL1 3 c D N ND 2 2
17 F 16 ND ND c D N ND 1 1
18 M 24 ND 3 c D N ND 2 2
19 F 17 ND ND c D N ND 1 1
20 M 15 ND 3 c ND ND ND ND ND
21 F 15 ND 3 c ND ND ND ND ND
22 M 30 ND ND c D N ND 2 2

M: male; F: female; D: done; ND: not done; N: normal; aN: abnormal; SR: radiologist SR; SM: radiologist SM; MRI: magnetic resonance imaging.

UPSIT (according to R.L. Doty): 0: normosmia; 1: mild hyposmia; 2: severe hyposmia; 3: anosmia.

STOE (suprathreshold olfactory evaluation): a: normosmia; b: hyposmia; c: anosmia.

OB (olfactory bulb): 0: OB normal; 1: OB hypoplasia; 2: OB aplasia.