Table 1: The comparison of HFNCO and NIV systems.
| HFNCO | NIV |
| Fixed flow and variable pressure levels | Variable flow for fixed pressure |
| Able to reduce dead space | Increases dead space |
| Does not effect tidal volume | May increase tidal volume |
| Reduces respiratory workload | More effective in reducing respiratory workload |
| Minimal gastric distention | Loss of pressure when mouth is opened |
| Pressure can be maintained |