Table 2: Characteristics
of elderly patients (≥75 years) in the RICA registry with atrial
fibrillation and congestive heart failure by ejection fraction
Variable |
n |
< 45% |
≥45% |
p |
Number |
851 |
216 |
635 |
|
Age |
216/635 |
82.3 (4.6) |
82.5 (4.5) |
0.440 |
Sex (male,%) |
216/635 |
58.3 |
34.5 |
< 0.001 |
Charlson index |
216/635 |
4.5 (2.9) |
3.5 (2.4) |
< 0.001 |
Barthel
index |
212/615 |
81.2 (20.7) |
79.8 (21.9) |
0.430 |
Body mass index |
216/635 |
26.7 (4.4) |
28.4 (5.1) |
< 0.001 |
Heart rate |
216/635 |
89.7 (23.9) |
88.3 (24.5) |
0.454 |
Systolic blood pressure (mmHg) |
216/635 |
133.0 (26.4) |
140 (23.7) |
< 0.001 |
Diastolic blood pressure (mmHg) |
216/635 |
74.1 (15.6) |
76.4 (17.6) |
0.127 |
History |
|
|
|
|
Arterial
hypertension (%) |
216/635 |
88.9 |
86.1 |
0.352 |
Diabetes
mellitus (%) |
216/635 |
41.2 |
40.6 |
0.936 |
Smoking (%) |
216/635 |
5.1 |
3.9 |
0.440 |
Hyperlipidaemia
(%) |
216/635 |
50.0 |
40.2 |
0.013 |
COPD (%) |
216/635 |
32.9 |
24.7 |
0.021 |
Chronic
renal failure (%) |
216/635 |
39.8 |
31.0 |
0.019 |
Prior
myocardial infarction (%) |
216/635 |
37.5 |
14.0 |
< 0.001 |
NYHA (%) |
|
|
|
|
I |
5/29 |
2.3 |
4.6 |
0.428 |
II |
110/307 |
51.2 |
48.5 |
|
III |
87/266 |
40.5 |
42.0 |
|
IV |
13/31 |
6.0 |
4.9 |
|
I-II |
100/297 |
46.3 |
46.8 |
0.937 |
III-IV |
116/338 |
53.7 |
53.2 |
|
Laboratory parameters, mean (SD) |
|
|
|
|
Haemoglobin
(mg/dl) |
216/635 |
12.2 (1.8) |
11.9 (1.9) |
0.149 |
Creatinine
(mg/dl) |
216/635 |
1.4 (0.6) |
1.4 (3.5) |
0.873 |
MDRD
(ml/min/1.73m2) |
216/635 |
55.4 (23.8) |
55.8 (23.6) |
0.809 |
C-reactive
protein (mg/dl) |
118/331 |
18.8 (44.2) |
22.9 (39.1) |
0.337 |
BNP (pg/ml) |
38/102 |
1265 1001) |
834 (826) |
0.033 |
Pro-BNP
(pg/ml) |
83/275 |
8478 (9644) |
6154 (13014) |
0.133 |
Sodium
(mEq/l) |
216/635 |
139.3 (4.4) |
138.9 (4.8) |
0.281 |
Potassium
(mEq/l) |
205/611 |
4.3 (0.5) |
4.3 (0.6) |
0.238 |
Uric acid
(mg/dl) |
131/385 |
7.9 (2.6) |
7.8 (2.4) |
0.767 |
Electrocardiographic abnormalities (%) |
|
|
|
|
Left
ventricular hypertrophy |
216/635 |
28.7 |
27.4 |
0.725 |
Left bundle
branch block |
216/635 |
33.8 |
13.9 |
< 0.001 |
Right bundle
branch block |
216/635 |
7.9 |
15.0 |
0.007 |
Echocardiographic characteristics,
mean (SD) |
|
|
|
|
Ejection
fraction (%) |
216/635 |
33.6 (6.8) |
60.4 (9.1) |
< 0.001 |
Left atrial
dimension (mm) |
151/429 |
49.3 (7.6) |
49.0 (9.1) |
0.761 |
Posterior
wall thickness (mm) |
40/155 |
15.8 (6.6) |
11.9 (2.6) |
0.019 |
Mitral
regurgitation, moderate-severe |
203/584 |
38.9 |
22.1 |
< 0.001 |
Treatment |
|
|
|
|
Betablockers |
216/635 |
68.1 |
56.2 |
0.002 |
Diuretics |
216/635 |
91.2 |
90.4 |
0.788 |
ACEI- RAA |
216/635 |
78.2 |
73.9 |
0.205 |
Spironolactone |
216/635 |
46.2 |
30.1 |
< 0.001 |
Digoxin |
216/635 |
36.6 |
39.8 |
0.420 |
Calcium
channel blocker |
216/635 |
11.6 |
24.9 |
< 0.001 |
Statin |
216/635 |
48.1 |
34.2 |
< 0.001 |
Antiplatelets |
216/635 |
35.2 |
20.9 |
< 0.001 |
Vitamin K
antagonists |
216/635 |
65.3 |
75.3 |
0.006 |
Mortality |
216/635 |
26.4 |
21.6 |
0.159 |
COPD:
Chronic Obstructive Pulmonary Disease, LV: Left Ventricular End-Diastolic
Volume, RV:
Right Ventricular End-Diastolic Volume, PAP: Pulmonary Arterial Pressure,
ACEI-RAA: Angiotensin-Converting Enzyme Inhibitor, Renin-Angiotensin Antagonist