Table 4: General characteristics of patients
depending on the concentrations of MR-proADM stratified into quartiles.
Quantitative variables.
Variable |
n |
I
Quartil |
II
Quartil |
III
Quartil |
IV
Quartil |
P value* |
Personal characteristics |
||||||
Age (median) |
191 |
79 (20) |
80 (12) |
77 (15) |
77 (11) |
ns |
BMI (mean) |
173 |
30.74 ± 9.01 |
31.28 ± 7.14 |
29.85 ± 5.73 |
30.51 ± 6.66 |
ns |
Vital status variables |
||||||
Glasgow (median) |
184 |
15 (3) |
15 (0) |
15 (1) |
15 (2t) |
ns |
MAP (median) |
181 |
94 (24) |
92 (22) |
92 (19) |
91 (27) |
ns |
H.R. (media) |
181 |
91 ± 18 |
90 ± 25 |
89 ± 22 |
91 ± 23 |
ns |
Temp. (median) |
181 |
36.4 (0.8) |
36.6 (0.9) |
36.5 (1) |
36.4 (0.7) |
ns |
Laboratory variables |
||||||
pH (mean) |
190 |
7.29 ± 0.1 |
7.28 ± 0.09 |
7.28 ± 0.1 |
7.27 ± 0.11 |
ns |
PaCO2 (median) |
191 |
66.07 (40.03) |
57.36 (26.4) |
54.36 (23.56) |
62.82 (18.5) |
ns |
HCO3- (mean) |
191 |
27.7 ± 6.4 |
24.5 ± 4.7 |
23.9 ± 5.6 |
25.1 ± 6.1 |
ns |
PaO2/FiO2
(mean) |
77 |
210 ± 102 |
208 ± 97 |
211 ± 118 |
231 ± 172 |
ns |
Lact. (median) |
182 |
1.5 (1.5) |
1.8 (1.7) |
1.8 (1.7) |
1.9 (2.1) |
ns |
Hb. (mean) |
191 |
12.4 ± 2.03 |
12.4 ± 2.02 |
12.9 ± 2.4 |
12.5 ± 2.2 |
ns |
Leuk. (mean) |
191 |
10.8 ± 4.5 |
11.7 ± 4.3 |
11.8 ± 4.4 |
12.7 ± 7.7 |
ns |
Plat. (median) |
191 |
251 (98) |
226 (96) |
232 (99) |
262 (128) |
ns |
Urea (median) |
191 |
49 (32) |
56 (47) |
58 (45) |
61 (53) |
ns |
Creat. (median) |
191 |
1.1 (0.6) |
1.5 (0.6) |
1.3 (0.8) |
1.5 (0.8) |
ns |
Na+ (median) |
191 |
139 (8) |
139 (7) |
138 (9) |
140 (8) |
ns |
K+ (median) |
177 |
4.6 (1.1) |
4.6 (0.8) |
4.6 (1.1) |
4.5 (1.3) |
ns |
INR (median) |
191 |
1.1 (0.5) |
1.1 (0.5) |
1.1 (0.4) |
1.2 (1) |
ns |
Abbreviations and measurement units: BMI: body-mass index; MAP: mean
arterial pressure (mmHg); H.R.: heart rate (beats per minute); Temp:
temperature (degrees Celsius); PaCO2: arterial carbon dioxide
tension (mmHg); HCO3-: bicarbonate in arterial blood (mmol/L);
PaO2/FiO2: arterial oxygen tension/fraction of inspired oxygen; Lact.: lactic
acid in arterial blood (mmol/L); Hb.: hemoglobin (gr/L); Leuk.: leukocytes
(x1000); Plat.: platelets (x1000); Serum urea (mg/dL); Creat.: serum creatinine
(mg/dL); Na+: sodium ion (mmol/L); K+: potassium ion
(mmol/L); INR: international normalized ratio; MR-proADM: mid-regional
proadrenomedullin (nmol/L); ns: not significant.
Note: The means are expressed with standard deviation and they
make reference to variables with normal distribution while the medians are
expressed followed (in parentheses) of the interquartile range and refer to
non-parametric variables.
*Comparisons between groups were
performed by the ANOVA test for normally distributed variables and Kruskal-Wallis
for non-parametric.