Table 5: Effect of ARBs and antidiabetic agents on liver functions during 3 consecutive follow up.
Parameter | ALT U/L | AST U/L | Albumin G/DL | |||||||
Antihypertensive agents | Antidiabetic agents | 1st | 2nd | 3rd | 1st | 2nd | 3rd | 1st | 2nd | 3rd |
ARBs | Insulin | 42.9 ± 10.2 | 37.7b ± 10.1 | 49.3 ± 14.4 | 30.4 ± 8.2 | 28.8 ± 7.2 | 36 ± 10.3 | 3.5b ± 0.2 | 3.4b ± 0.1 | 3.3b ± 0.2 |
Biguanide | 57.8 ± 11.8 | 51.1 ± 13.3 | 71.3 ± 16.4 | 47.7 ± 11.8 | 35.2 ± 10.1 | 41.1 ± 11.5 | 3.5b ± 0.2 | 3.4 ± 0.0 | 3.5 ± 0.0 | |
Biguanide + DPP-4 | 53.6 ± 14 | 72.1a ± 14.1 | 72.1 ± 15.2 | 44 ± 13 | 40.5 ± 10.9 | 45.1 ± 11.8 | 4.1a ± 0.1 | 3.8a ± 0.1 | 3.8a ± 0.1 |
Values represent mean ± SE.
Small alphabetical letter in the same column within the same parameters are significantly different between groups at P < 0.05 (Two way ANOVA).