|
Control group |
Cholesterol-fed non-treated group |
Cholesterol-fed treated with vildagliptin group |
Catalase Unita/mg tissue
Protein
|
66.32± 2.2 |
4.51± 0.32* |
54.7± 3.4** |
Glutathione
peroxidase
Unitb/mg tissue
Protein
|
12.23± 2.5 |
0.21± 0.02* |
17.34± 0.79** |
a=Moles of hydrogen peroxide consumed per minute.
b=µg of glutathione consumed per minute.
*P< 0.05, significant reduction in activity of both enzymes in cholesterol-fed non-treated group versus control group.
**P< 0.05, significant increase in activity of both enzymes by either drug or both of them versus cholesterol-fed non-treated group