Table 3: Mean ± SD changes in the activities of liver CAT, GPx in control and experimental albino mice expressed as unit/mg tissue protein of liver homogenates.

Control group Cholesterol-fed non-treated group Cholesterol-fed treated with vildagliptin group
Catalase Unita/mg tissue Protein 66.32± 2.2 4.51± 0.32* 54.7± 3.4**
Glutathione peroxidase Unitb/mg tissue Protein 12.23± 2.5 0.21± 0.02* 17.34± 0.79**

a=Moles of hydrogen peroxide consumed per minute.
b=µg of glutathione consumed per minute.
*P< 0.05, significant reduction in activity of both enzymes in cholesterol-fed non-treated group versus control group.
**P< 0.05, significant increase in activity of both enzymes by either drug or both of them versus cholesterol-fed non-treated group