Examples of FDA-approved medicaments that use spray drying technology as preparation method. HPMC: Hydroxypropyl Methylcellulose; HPMCAS: Hydroxypropyl Methylcellulose Acetate Succinate; DSPC: Distear-ylphosphatidylcholine (data summarized from [2-8]).

Table 1: Examples of FDA-approved medicaments that use spray drying technology as preparation method.

HPMC: Hydroxypropyl Methylcellulose; HPMCAS: Hydroxypropyl Methylcellulose Acetate Succinate; DSPC: Distear-ylphosphatidylcholine (data summarized from [2-8]).

Trade name	Drug	Application	Polymer, Excipient	Maximum drug dose	Company	FDA approval
Prograf	Tacrolimus	Immunosuppressant (prevents organ rejection)	HPMC	5 mg per capsule	Astellas Pharma	1994
Exhubera	Insulin	Diabetes	Mannitol, glycine, sodium citrate	1 or 3 mg per capsule	Pfizer/Nektar	2006
Intelence	Etravirine	HIV medicine	HPMC	100 or 200 mg per tablet	Janssen	2008
Zortress	Everolimus	Immunosuppressant (prevents organ rejection)	HPMC	0.75 mg per tablet	Novartis	2010
Aridol/Osmohale, Bronchitol	-	Asthma/Cystic fibrosis	Mannitol	5 to 40 mg per capsule	Pharmaxis	2010
Incivek	Telaprevir	Hepatitis C	HPMCAS	375 mg per tablet	Vertex	2011
Kalydeco	Ivacaftor	Cystic fibrosis	HPMCAS	150 mg per tablet	Vertex	2012
TOBI Podhaler	Tobramycin	Inhalation therapy	DSPC, calcium chloride, sulfuric acid	28 mg per capsule	Novartis	2013
Raplixa	-	Bleeding control during surgery	Fibrinogen/Thrombin	79 mg/726 IU per gram powder	Nova Laboratories	2016