Table 1: Key role and clinical outcome of CDC6 in different cancers.
Cancer types |
CDC6 expression |
Observation on clinical outcome |
References |
Brain cancer |
High expression |
Poor prognosis (oncogenic role) |
[25] |
Hepatocellular cancer |
High expression |
Poor prognosis (oncogenic role) |
[24] |
Gastric cancer |
High expression |
Poor prognosis (oncogenic role) |
[26,27] |
Prostate cancer |
High expression |
Poor prognosis (oncogenic role) |
[30,31] |
Pancreatic cancer |
High expression |
Poor prognosis (oncogenic role) |
[10] |
Lung cancer |
High expression |
Poor prognosis (oncogenic role) |
[28,56] |
Ovarian cancer |
High expression |
Poor prognosis (oncogenic role) |
[29] |
Breast cancer |
High expression |
Poor prognosis (oncogenic role) |
[17,35] |
Colorectal cancer |
High expression |
Poor prognosis (oncogenic role) |
[57] |
Bladder cancer |
High expression |
Poor prognosis (oncogenic role) |
[58] |
Chronic Myeloid leukaemia |
High expression |
Poor prognosis (oncogenic role) |
[32] |