Table 1: Clinical and demographic features of the study population before CT-scan.

PE

present

(n = 9)

non-present

(n = 39)

p-value

unclear

(n = 4)

Male: females

3:6 (33%:67%)

20:19 (51%:49%)

0.176

4:0 (100%:0%)

Age (y)

69.4 [62.1-79.8]

67.7 [61.8-79.0]

0.355

67.8 [61.6- 72.0]

Non-Caucasian race

2 (22.2%)

14 (35.9%)

0.216

3 (75%)

Risk factor:

Wells-Score ≥ 4

3 (33.3%)

15 (38.5%)

0.393

3 (75%)

Bed rest

5 (55.6%)

14 (35.9%)

0.213

3 (75%)

Previous VTE

2 (22.2%)

1 (2.6%)

0.112

0 (0%)

Active cancer

2 (22.2%)

6 (15.4%)

0.337

1 (25%)

Obesity

5 (55.6%)

25 (64.1%)

0.333

1 (25%)

CT-Indication:

CT-datum after admission(d)

15.22 [2-6]

6 [0-5.5]

0.121

14 [4-22]

Respiratory worsening

6 (66.7%)

25 (64.1%)

0.446

3 (75%)

 

Low O2 Saturation on ambient air

2 (22.2%)

14 (35.9%)

0.213

2 (50%)

Dyspnoea

3 (33.3%)

12 (30.7%)

0.445

2 (50%)

 

Tachypnoea

3 (33.3%)

4 (10.3%)

0.108

2 (50%)

Intubated

3 (33.3%)

9 (23.1%)

0.290

2 (50%)

Respiratory asymptomatic

3 (33.3%)

14 (35.9%)

0.446

0 (0%)

 

Chest Pain

0 (0.0%)

2 (5.2%)

0.080

0 (0%)

Infect focus

0 (0.0%)

3 (7.7%)

0.042

0 (0.0%)

Elevated
D-Dimer

0 (0.0%)

3 (7.7%)

0.042

0 (0.0%)

Other CT-indications

3 (33.3%)

6 (15.4%)

0.167

0 (0%)

Setting:

Intensive Care Unit

3 (33.3%)

8 (20.5%)

0.244

2 (50%)

Intermediate Care Unit

1 (11.1%)

7 (17.9%)

0.300

1 (25%)

Standard Care Unit

5 (55.6%)

24 (61.5%)

0.381

1 (25%)

Medication

Steroids

5 (55.6%)

17 (43.6%)

0.274

3 (75%)

Antiaggregant

Aspirin

1 (11.1%)

7 (17.9%)

0.300

1 (25%)

Other

0 (0%)

4 (10.3%)

0.022

0 (0%)

Heparin doses

Regular prophylactic

0 (0%)

6 (15.4%)

0.006

1 (25%)

 

Duration (in days)

-

7 [2.25-9.75]

 

5

Therapeutic

5 (55.6%)

16 (41.0%)

0.233

3 (75%)

 

Duration (in days)

22.4 [2-25]

9.8[2-8]

0.188

17 [10-25]

DOAC

1 (11.1%)

4 (10.3%)

0.473

0 (0%)

D-Dimer (μg/L)

< 500

0 (0%)

0 (0%)

0

0 (0%)

500-1500

1 (11.1%)

12 (30.8%)

0.081

2 (50%)

1500-4000

4 (44.4%)

12 (30.8%)

0.244

0 (0%)

> 4000

1 (11.1%)

6 (15.4%)

0.370

1 (25%)

Platelet < 150.000

2 (22.2%)

5 (12.8%)

0.281

0 (0%)

Gasometry

PaO2/FiO2 ratio (mmHg)

< 100

1 (11.1%)

3 (7.7%)

0.390

0 (0%)

100-200

1 (11.1%)

3 (7.7%)

0.390

0 (0%)

> 200

2 (22.2%)

12 (30.8%)

0.307

3 (75%)

pCO2 (mmHg)

< 35

0 (0%)

7 (17.9%)

0.003

1 (25%)

Infect burden on CT-Scan

Severe

4 (44.4%)

14 (35.9%)

0.333

2 (50%)

Moderate

0 (0.0%)

10 (25.6%)

< 0.05

2 (50%)

Mild

3 (33.3%)

13 (33.3%)

0.5

0 (0%)

No infiltrate

2 (22.2%)

2 (5.2%)

0.144

0 (0%)