Table 1: Study characteristics.
Reference |
Study population |
Study type |
ARDS etiology |
Primary outcome |
Secondary outcome |
Study quality |
Mean duration of PP |
Beuret, et al. |
51 patients aged 54 (mean) |
RCT |
Only pneumonia listed |
Incidence of lung worsening defined by an increase in the Lung Injury, Score of at least 1 point |
Incidence of VAP |
Fair |
4 h daily for 6.0 d |
Manecebo, et al. |
136 patients aged 37-71 |
RCT |
Pneumonia, aspiration, sepsis, multiple trauma |
ICU mortality |
Hospital mortality, associated complication, and length of stay |
Good |
17 h daily for 10.1 d |
Fernandez, et al. |
40 patients aged 36-72 |
RCT |
Only lists pulmonary and extra-pulmonary ARDS |
Not specifically expressed. Outcomes noted were: Mortality, ICU length, mechanical ventilation days, hospital stay, and adverse events |
Not specifically expressed, Outcomes noted were: Mortality, ICU length, mechanical ventilation days, hospital stay, and adverse events |
Fair |
18 h daily |
Guérin, et al. |
466 patients aged 42-74 |
RCT |
Being comatose leading to pulmonary infection and closure of small airways with alveolar atelectasis |
Mortality at day 28 |
Mortality at day 90, rate of successful extubation, time to successful extubation, length of ICU stay and complications |
Good |
17 h daily for 4 d |