Table 2: Comparison of clinical characteristics of patients with mild and
moderate-severe community-acquired pneumonia (CAP)
|
Characteristic
|
All patients With CAP (n = 209) |
Patients with mild CAP (n = 53) |
Patients with moderate-severe CAP (n = 156) |
p-value |
|
Age
(years)
|
71.36
± 12.93 |
62.08
± 14.81 |
74.36
± 10.78 |
<
0.0001 |
|
Gender |
|
|
|
0.34 |
|
Male |
107
(51.20%) |
24
(45.28%) |
83
(53.21%) |
|
|
Female |
102
(78.80%) |
29
(54.72%) |
73
(46.79%) |
|
|
Co-morbid
Conditions |
|
|
|
|
|
Chronic
heart disease |
164
(78.47%) |
32
(60.38%) |
132
(84.62%) |
<
0.0001 |
|
Chronic
lung disease |
80
(38.28%) |
18
(33.95%) |
62
(39.74%) |
0.52 |
|
Cancer
|
47
(22.49%) |
5
(9.43%) |
42
(26.92%) |
0.01 |
|
Neurologic
disease |
50
(23.92%) |
4
(7.55%) |
46
(29.49%) |
0.001 |
|
Chronic
renal disease |
48
(22.97%) |
4
(7.55%) |
44
(28.21%) |
0.001 |
|
Patients
from LTCF |
33
(15.79%) |
2
(3.77%) |
31
(19.87%) |
0.004 |
|
Systemic
steroids use
|
57
(27.27%) |
16
(30.19%) |
41
(26.28%) |
0.60 |
|
Duration
of symptoms before presentation (days) |
4.94
± 5.26 |
5.10
± 5.04 |
4.95
± 5.44 |
0.86 |
|
Hospitalization
in last 90 days |
39
(18.75%) |
4
(7.55%) |
35
(22.58%) |
0.02 |
|
Weekend
admission |
67
(32.06%) |
18
(33.96%) |
49
(31.41%) |
0.74 |
|
Time
to first appropriate antibiotic since time of triage (hours) |
6.16
± 7.94 |
4.60
± 3.43 |
6.62
± 9.01 |
0.02 |
|
First
appropriate antibiotic >4hours
since time of triage |
96
(45.93%) |
23
(43.04%) |
73
(46.79%) |
0.75 |
|
Time
to first appropriate antibiotic since time of physician assessment (hours) |
4.50
± 4.73 |
3.21
± 3.13 |
4.80
± 5.08 |
0.02 |
|
Time
seen by physician since time of triage (hours) |
1.0 ± 1.20 |
1.19 ± 1.24 |
0.95 ± 1.20 |
0.25 |
|
Duration
of antibiotics(days) |
10.79 ± 4.20 |
9.91 ± 2.63 |
11.05 ± 4.61 |
0.03 |
|
Length
of hospital stay (days) |
9.47
± 9.70 |
6.42
± 5.79 |
10.48
± 10.53 |
0.001 |
|
Patients
on macrolide |
115
(55.02%) |
35
(66.04%) |
80
(51.28%) |
0.08 |
|
Patients
on fluoroquinlones |
56
(26.79%) |
13
(24.53%) |
43
(27.56%) |
0.72 |
|
Positive culture (respiratory or blood) |
22
(10.53%) |
9
(16.98%) |
13
(8.33%) |
0.13 |
|
Complications |
91
(43.54%) |
10
(18.87%) |
81
(51.92%) |
<
0.0001 |
|
Complications
within 24 hours of admission |
60
(28.71%) |
6
(11.32%) |
54
(34.62%) |
0.001 |
|
Complications
after 24 hours of admission |
65
(31.10%) |
6
(11.32%) |
59
(37.82%) |
0.0002 |
|
Cardiac
complications |
17
(8.13%) |
4
(7.55%) |
13
(8.33%) |
1.00 |
|
Respiratory
failure |
41
(19.61%) |
1
(1.89%) |
40
(25.64%) |
<
0.0001 |
|
Septic
Shock |
4
(1.91%) |
0 |
4
(2.56%) |
0.57 |
|
Empyema
|
1
(0.48%) |
0 |
1
(0.46%) |
1.000 |
|
Cardiac
ischemia |
7
(3.35%) |
1
(1.89%) |
6
(3.85%) |
0.68 |
|
Arrhythmias
|
12
(5.74%) |
3
(5.66%) |
9
(5.77%) |
1.000 |
|
Intensive
care admission |
25
(11.96%) |
0 |
25
(16.03%) |
0.001 |
|
Others
complications |
28
(13.40%) |
4
(14.29%) |
24
(15.48%) |
0.17 |
|
Death |
32
(15.31%) |
1
(1.89%) |
31
(19.87%) |
0.001 |
LTCF:
long term care facility
Data expressed as mean ± SD or frequency and percentage as indicated.