Table 5: Univariate analysis for aGVHD and cGVHD.
Characteristic | aGVHD grades 3-4 | Extensive cGVHD |
---|---|---|
Age | 0.002* | 0.03* |
Gender | 0.04* | 0.2 |
Cytogenetic at diagnosis | 0.6 | 0.3 |
Stage of disease before alloSCT | 0.8 | 0.6 |
RIC Conditioning | 0.01a | 0.1 |
GvHD Prophylaxis | 0.7 | 0.05a |
Donor age | 0.005a | 0.01a |
Donor gender | 0.6 | 0.9 |
Transplant, CD34+ | 0.4 | 0.2 |
WBC engraftment | 0.2 | 0.1 |
Platelets engraftment | 0.9 | 0.6 |
Chimerism at day +28 after alloSCT | 0.7 | 0.09 |
Chimerism at day +56 after alloSCT | 0.7 | 0.5 |
Chimerism at day +100 after alloSCT | 0.06 | 0.001a |
Chimerism at 1 year after alloSCT | 0.7 | 0.3 |
Chimerism at the end of observation | 0.8 | 0.2 |
GvHD: Graft Versus Host Disease; aGvHD: Acute GvHD; cGvHD: Chronic GvHD; TRM: Treatment Related Mortality; aSignificant, P value < 0.05.