Table 1: Salivary inorganic protective components in patients
with reflux esophagitis (RE) and control group (CTRL) (Mean ± SEM)
Parameter |
Basal |
Mastication |
Tubing |
Balloon |
Initial NaCl |
HCl |
HCl/pepsin |
Final NaCl |
Volume RE (ml/min) |
0.57± 0.09 |
1.32 ± 0.20 |
2.27 ± 0.50 |
2.68 ± 0.47 |
2.84 ± 0.49 |
3.06 ± 0.54 |
3.23 ± 0.53 |
2.91 ± 0.50 |
Volume CTRL (ml/min) |
0.52± 0.05 |
1.43 ± 0.12 |
2.51 ± 0.27 |
3.16 ± 0.32 |
2.94 ± 0.29 |
3.68 ± 0.41 |
2.83 ± 0.33 |
2.75 ± 0.33 |
pH RE |
7.03 ± 0.10 |
7.44 ± 0.08 |
7.72 ± 0.09 ⃰ |
7.70 ± 0.08 |
7.70 ± 0.08 ⃰ |
7.58 ± 0.11⃰ |
7.66 ± 0.10⃰ ⃰ |
7.66 ± 0.09⃰ ⃰ |
pH CTRL |
7.14 ± 0.09 |
7.63 ± 0.08 |
8.02 ± 0.06 |
7.93 ± 0.09 |
8.01 ± 0.08 |
7.90 ± 0.09 |
8.14 ± 0.08 |
7.92 ± 0.18 |
Bicarbonate RE (µmol/min) |
3.38 ± 1.10 |
12.30± 3.04 |
28.30 ± 6.95 ⃰ |
61.00± 19.20 |
56.90± 25.00 |
64.90± 21.50 |
50.00± 15.70 |
51.40± 16.10 |
Bicarbonate CTRL (µmol/min) |
4.13 ± 0.86 |
17.90± 2.37 |
94.20± 35.18 |
97.80± 29.26 |
75.20± 16.3 |
77.90± 11.82 |
59.00± 11.98 |
48.40± 10.39 |
Non-Bicarbonate RE (µmol/min) |
4.35 ± 1.28 |
12.50± 2.70 |
18.60± 5.04 |
14.50± 3.17 |
23.10± 6.75 |
18.60± 4.56 |
24.40± 4.68 |
16.90± 2.61 |
Non-Bicarbonate CTRL (µmol/min) |
4.42 ± 1.07 |
11.60± 1.60 |
18.10± 3.99 |
19.10± 4.43 |
24.93 ± 6.38 |
21.80± 4.97 |
18.50± 4.79 |
17.60± 4.01 |
* = p<0.05; **= p<0.01 respectively,
significant p values in patients with RE when compared to CTRL group.