Table 3: Risk factors associated with incidence of subsequent AKI.
|
|
Univariate |
Multivariate |
||
|
HR (95% CI) |
P value |
aHR (95% CI) |
P value |
|
|
Age: < 6 yr vs. ≥ 6 yr |
0.95 (0.41-2.2) |
0.91 |
|
|
|
Female vs. Male |
1.76 (0.74-4.2) |
0.20 |
|
|
|
Weight (kg) |
0.99 (0.97-1.02) |
0.67 |
|
|
|
BSA (m2) |
0.8 (0.28-2.28) |
0.68 |
|
|
|
Coexisting conditions |
|
|
|
|
|
Cardiovascular |
2.12 (0.71-6.31) |
0.18 |
|
|
|
Pulmonary |
0.72 (0.21-2.47) |
0.60 |
|
|
|
Hematologic |
1.25 (0.29-5.35) |
0.77 |
|
|
|
AKI stage at enrollment |
|
|
|
|
|
No AKI |
Ref |
|
|
|
|
AKI stage 1 |
2.39 (0.92-6.16) |
0.07 |
|
|
|
AKI stage 2 |
1.05 (0.14-7.97) |
0.96 |
|
|
|
Non-surgical vs. Surgical group |
2.69 (0.91-7.98) |
0.07 |
2.49 (0.15-40.59) |
0.52 |
|
Creatinine: ≥ 0.5 vs. < 0.5 |
3.34 (1.22-9.14) |
0.02 |
2.32 (0.81-6.64) |
0.12 |
|
eGFR: < 90 vs. ≥ 90 |
2.25 (0.3-16.84) |
0.43 |
|
|
|
RAI: ≥ 8 vs. < 8 |
7.13 (1.67-30.57) |
0.01 |
11.44 (1.15-114.07) |
0.04 |
|
Hb: < 11 vs. ≥ 11 |
3.83 (1.29-11.35) |
0.02 |
3.37 (1.06-10.75) |
0.04 |
|
NLR: ≥ 3 vs. < 3 |
0.81 (0.33-1.95) |
0.63 |
|
|
Data are presented as number (%).
HR: Hazard Ratio; aHR: adjusted Hazard Ratio; CI: Confidence Interval; AKI: Acute Kidney Injury; eGFR: estimated Glomerular Filtration Rate; RAI: Renal Angina Index; Hb: Hemoglobin; NLR: Neutrophil-to-Lymphocyte Ratio