Table 3: Associations between the Top Imputed
SNP in Each Gene with Good Imputation Quality (r2 >
0.8) and EOC Incidence Overall.
Gene |
SNP |
Min/Maj |
MAF |
OR (95%
CI) |
p |
BMAL1 |
rs117104877 |
G/A |
0.017 |
0.79
(0.68-0.90) |
5.59
× 10-4 |
CRY2 |
rs10838527 |
G/A |
0.082 |
1.05
(0.99-1.11) |
7.66
× 10-2 |
CSNK1E |
rs111427515 |
G/T |
0.008 |
1.25
(1.06-1.47) |
6.60
× 10-3 |
KLF10 |
rs2511699 |
A/G |
0.461 |
0.96
(0.93-0.99) |
4.13
× 10-3 |
NPAS2 |
rs732375 |
T/A |
0.134 |
1.07
(1.02-1.11) |
3.76
× 10-3 |
PER3 |
rs228640 |
A/G |
0.297 |
1.04
(1.01-1.07) |
1.24
× 10-2 |
REV1 |
rs3792146 |
T/C |
0.547 |
1.03
(1-1.06) |
2.71
× 10-2 |
SENP3 |
rs143094271 |
A/G |
0.023 |
0.86
(0.77-0.95) |
4.01
× 10-3 |
TIMELESS |
rs2638286 |
C/T |
0.030 |
1.05
(0.96-1.15) |
2.56
× 10-1 |
SNP: Single Nucleotide
Polymorphism, Min/Maj: Minor and Major Allele, MAF: Minor Allele Frequency, OR:
Odds Ratio
Note: odds
ratio is calculated based on per-minor allele