BRCA1/2 mutations from nine human cell lines.

Table 1: BRCA1/2 mutations from nine human cell lines.

Sample ID	Gene	Exon/intron	HGVS ID, cDNA	Amino acid change	Allele frequency	Interpretation
HCC1395	BRCA1	ex 20	NM_007294.3:c.5251C > T	R1751*	0.940	5-Pathogenic
HCC1569	BRCA2	ex 11	NM_000059.3:c.5583del	V1862*	0.230	5-Pathogenic
HCC1937	BRCA1	ex 20	NM_007294.3:c.5266dup	E1756fs*74	0.990	5-Pathogenic
MDA-MB-436	BRCA1	in 20	NM_007294.3:c.5277+1G > A	N/A	0.997	5-Pathogenic
BT474	BRCA2	ex 25	NM_000059.3:c.9281C > A	S3094*	0.660	5-Pathogenic
CAL51	BRCA2	ex 11	NM_000059.3:c.2957del	N986 fs*5	0.220	5-Pathogenic
LS180	BRCA2	ex 23	NM_000059.3:c.9097del	T3033fs*29	0.530	5-Pathogenic
HCT116	BRCA2	ex 18	NM_000059.3:c.8021dup	I2675fs*6	0.480	5-Pathogenic
HCT15	BRCA2	ex 11	NM_000059.3:c.3599_3600del & NM_000059.3:c.5351del	C1200* & N1784 fs*7	0.280 0.490	5-Pathogenic 5-Pathogenic