Table 6: Univariate and multivariate analysis of factors for vulnerability associated with severe COVID-19 (Stage 4 or 5).
|
Univariate Analysis |
Multivariate Analysis |
|
Variable |
Severe COVID-19 (%) |
OR (95% CI) p-value |
OR (95% CI) p-value |
Male |
16.6 |
1.09 (0.76-1.55) 0.643 |
- |
Age ≥ 80 years |
22.6 |
1.96 (1.37-2.80) < 0.001 |
1.60 (1.08-2.37) 0.019 |
Severe functional impairment (Katz Index ≤ 2) |
24.0 |
1.83 (1.11-3.00) 0.016 |
1.30 (0.75-2.25) 0.346 |
Frailty with dependence (CFS ≥ 5) |
20.2 |
1.71 (1.20-2.42) 0.003 |
1.30 (0.86-1.97) 0.208 |
COVID-19 Decision Support Tool (Points ≥ 9) |
17.3 |
1.96 (1.15-3.35) 0.012 |
1.32 (0.73-2.39) 0.350 |
Multiple Co-morbidities (CCI ≥ 3) |
16.2 |
1.84 (0.65-5.23) 0.247 |
- |
Presence of delirium/cognitive impairment (4AT ≥ 4) |
18.6 |
1.39 (0.78-2.47) 0.268 |
- |
Polypharmacy (≥ 5 medications) |
14.4 |
0.84 (0.58-1.21) 0.348 |
- |
OR: Odds Ratio; CI: Confidence Interval