Table
6:
Primary and secondary outcomes based on HBP* and CBP** at end-point in 96
overweight patients with type 2 diabetes mellitus.
|
Outcomes |
Patient
status: HBP* end-point in
96 overweight patients |
Patient status:
CBP** at end-point in 96 overweight patients |
||||||
|
|
Hypertension (n = 30) |
Normotension (n = 66) |
Hazard ratio (95% CI) |
P |
Hypertension (n = 42) |
Normotension (n = 54) |
Hazard ratio (95% CI) |
P |
|
Primary outcome |
|
|||||||
|
Death |
13 |
8 |
3.6 (1.7-10.5) |
0.0244 |
12 |
9 |
1.6 (0.7-3.7) |
0.2976 |
|
Secondary outcome |
|
|||||||
|
Microvascular
complications |
21 |
34 |
2.1 (1.8-6.6) |
0.0010 |
16 |
31 |
1.0 (0.5-1.8) |
0.9496 |
|
Macrovascular
complications |
9 |
6 |
3.2 (1.3-11.0) |
0.0184 |
7 |
8 |
1.1 (0.6-3.0) |
0.8795 |
The overweight
was defined by as the criteria of Japan Society for the Study of Obesity. Body
mass Index (BMI) with from < 25.0 kg/m2 to < 30 kg/m2 was
defined as overweight. The 400 patients in each group were classified as having
overweight and hypertension or normotension according to values of blood pressure as same
threshold with less than 130 mmHg of systolic blood pressure measured in the
home (HBP*) and in the clinic (CBP**) at end-point, respectively. Differences
in primary and secondary outcomes for events between overweight patients with
hypertension and normotension measured at end-point
in each group were assessed using survival curves from the Kaplan-Meier method,
and comparisons were analyzed using hazard ratio by
the log-rank test. CI, confidence interval. Two-tailed values of P < 0.05
were defined as statistically significant