**Table 1:** Demographics and echocardiographic characteristics of the study populations.

HyperGEN (N = 1,934) | GENOA (N = 1,090) | P* | |
---|---|---|---|

Age, years | 46.3 ± 13.2 | 61.8 ± 10.1 | < 0.0001 |

Female, % | 63.10% | 71.30% | < 0.0001 |

Body mass index, kg/m2 | 32.0 ± 7.7 | 31.6 ± 6.6 | 0.13 |

Centers in Alabama, % | 75.20% | 0% | < 0.0001 |

Hypertension, % | 65.70% | 82.30% | < 0.0001 |

Diabetes, % | 20.10% | 30.50% | < 0.0001 |

Left ventricular traits |
|||

Left ventricular mass, g | 170.2 ± 49.4 | 160.0 ± 44.6 | < 0.0001 |

Left ventricular internal dimension-diastole, cm | 5.2 ± 0.5 | 5.2 ± 0.5 | 0.99 |

Relative wall thickness | 0.34 ± 0.06 | 0.32 ± 0.05 | 0.003 |

Fractional shortening, % | 33.3 ± 5.5 | 32.9 ± 4.6 | 0.003 |

The ratio of left ventricular transmitral early velocity to late/atrial velocity | 1.2 ± 0.5 | 1.1 ± 0.38 | < 0.001 |

Left atrial dimension, cm | 3.4 ± 0.5 | 3.6 ± 0.5 | < 0.001 |

^{*}Numeric variables were presented as mean ± SD, categorical variables were presented as percentages. Significance determined using Chi-square test for categorical and two independent sample t-test for continuous.