Table 7: Suppressive and prophylactic antiplasmodial activities of Chromolena odorata leaf extract on parasitized mice.
|
Treatment ( mg/kg) |
Suppressive % Parasitemia |
% Inhibition |
Prophylactic % Parasitemia |
% Inhibition |
|
PCO |
32.35 ± 3.16 |
- |
28.99 ± 2.02 |
- |
|
CQ 10 |
1.22 ± 0.45a |
96.23 |
1.10 ± 0.08a |
96.21 |
|
CO 250 |
4.62 ± 0.67ab |
85.71 |
3.35 ± 0.29ab |
88.44 |
|
CO 500 |
2.21 ± 0.83ab |
93.17 |
1.70 ± 0.46ab |
94.14 |
|
CO 1000 |
1.27 ± 0.61a |
96.07 |
1.12 ± 0.08a |
96.14 |
NCO: Parasitized Control; CQ: Chloroquine, CO: Chromolaena odorata Extract; Data as mean ± SEM (Standard error of mean); aSignificant different (p < 0.05) when compared to Parasitized control; bSignificant different (p < 0.05) compared to CQ.