Table 1: Previous reports of cellulitis with Achromobacter xylosoxidans denitrificans, detail in type of infection, antimicrobial resistance, and treatment.

Year reported

Age/Sex

Type of infection

Isolation specimen

Comorbid conditions

Predisposing factors

Resistance Profile

Antibiotic of choice

Treatment duration

Outcome

1988, Spear JB, et al. [9]

79/F

Bacteremia, cellulitis (flank)

Blood, deep wound exudate, well water

Metastatic breast carcinoma, treatment with hydrocortisone

Ingestion of well water

The patient's home drinking water was identified as the source of infection

GE, AMK, CFPM

 

TMP-SMX, IMI/CS+PN

Few days

Died

1991, San Miguel VV, et al. [11]

41/M

Bacteremia, septic arthritis, and recurrent cellulitis (ankle, knee, wrist)

Blood, synovial fluid

Systemic lupus erythematous

Ingestion of well water

Not reported

PIP, 3.ceftazidime

1. 14 days

2. 1 month

3. Not reported

Cured

2014, Tena D, et al. [4]

73/M

Wound infection, cellulitis (foot)

Wound exudate

Parkinson disease, obesity, alcoholism, deep vein thrombosis

Chronic vascular insufficiency, trauma

PIPC/TAZ,  TMS/SMX, IMI/CS

AMCL

 

Cured

2015, Dai J, et al. [5]

20/M

Cellulitis of the left neck, bulky lymphadenitis and bacteremia

Culture of a neck aspirate, blood

ALL

Reinduction chemotherapy

AMK, GM, CFPM, CIFX

AMK and IMI/CS

3 days

Died

2015, Pamuk G, et al. [6]

15/F

Ankle osteomyelitis complicating superficial thrombophlebitis

Blood

No

Ankle local trauma

Not reported

MEPM and AMK

4 weeks

Cured

2021, Oyama Y, et al. [7]

49/M

Cellulitis on left leg.

 

Blood, exudate culture

Relapsed AML

HSCT

AMK, AZT, GM, CFPM

 

MEPM, PIPC/TAZ

2 weeks

Cured

2016, Kikuchi T, et al. [8]

80/M

Cellulitis and bacteremia

Blood

MM

Bortezomib therapy

CFPM, AMK, CPFX

MEPM

2 weeks

Cured