Table 1: Some relevant clinical features of the patients included (33 cirrhotics and 37 non-cirrhotics). In addition to mean ± standard deviation, median value and interquartile range are given for those variables with a non-parametric distribution.
| Cirrhotics (n = 33) | Non-cirrhotics (n = 37) | Student´s t test or mann-whitney test (Z) | Controls (n = 13) | |
| Age (years) | 60.12 ± 10.09 | 58.03 ± 12.04 | T = 0.97; NS | 55.75 ± 9.32 |
| Daily consumption (g) | 191 ± 118 | 175 ± 92 | T = 0.66; NS | < 10 |
| Years of addiction | 35 ± 12 | 34 ± 12 | T = 0.85; NS | --------- |
| Mean corpuscular volume (fl) | 102.4 ± 9.0 | 100.6 ± 6.2 | T = 2.08; p = 0.041 | Normal range = 77-91 |
| Serum GGT (U/l) | 359 ± 772 172 (51-362) |
205 ± 242 85 ( 62-210) |
Z = 1.03; NS | Normal range = 7-40 |
| Serum ASAT (U/l) | 82.8 ± 109.1 50 (30-93) |
64.9 ± 118 29 (19-43) |
Z = 2.77; p = 0.006 | Normal range = 7-40 |
| Serum ALAT (U/l) | 58.6 ± 74.9 32 (17-58) |
52.2 ± 76.1 28 (14-53) |
Z = 1.36; NS | Normal range = 7-40 |
| Prothrombin activity (%) | 66.9 ± 18.2 | 91.2 ± 12.5 | T = 7.44; p < 0.001 | Normal range = 80-100 |
| Serum albumin (g/dl) | 3.25 ± 0.76 | 3.73 ± 0.60 | T = 3.26; p = 0.002 | Normal range = 3.8-4.5 |
| Serum bilirubin (mg/dl) | 3.22± 3.46 2.30 (1.00-4.20) |
1.39 ± 2.15 1.00 (1.00-1.00) |
Z = 4.83; p < 0.001 | Normal range = < 1.4 |
| Serum creatinine (mg/dl) | 1.09± 0.73 0.80 (0.65-1.10) |
0.73 ± 0.27 0.71 (0.65-0.88) |
Z = 1.54; NS | Normal range = 0.5-1.1 |
| Platelet count (× 109/l) | 127.4 ± 74.0 128 (76-162) |
217.8 ± 74.7 209 (173-281) |
Z = 5.03; p < 0.001 | Normal range = 150-400 |
| Sclerostin (pmol/l) | 63.71 ± 47.63 | 36.81± 30.47 | T = 2.85; p = 0.006 | 47.62 ± 20.32 |