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Journal of
Obesity and Weight-loss Medication ISSN: 2572-4010

Citation

Callender CO, Mwendwa DT, Gholson G, Wright RS, Larry KII, et al. (2019) BMI, Waist Size, GFR: In African American Blacks. J Obes Weight-Loss Medic 5:028. doi.org/10.23937/2572-4010.1510028

Copyright

© 2019 Callender CO, et al.This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

RESEARCH ARTICLE | OPEN ACCESS DOI: 10.23937/2572-4010.1510028

BMI, Waist Size, GFR: In African American Blacks

Clive O Callender, MD1*, Denee T Mwendwa, PhD2, Georica Gholson, PhD3, Regina Sims Wright, PhD4, Larry Keen II, PhD5, Babwande Adesibikan, MD1, Serge Madhere, PhD2, Victor Apprey, PhD6, George Bonney, PhD6, Miriam Michael, MD7, Bomi Magnus-Lawson, MD7, Gabriel Ivy, MD8, Linda Idris-Suleiman, MD9, Arturo Hernandez, MD1, Olga Herren, MS2, and Alfonso L Campbell, PhD2

1Department of Surgery, Howard University School of Medicine, USA

2Department of Psychology, Howard University, USA

3Walter Reed National Military Medical Center, USA

4School of Nursing, University of Delaware, USA

5Department of Psychology, Virginia State University, USA

6Department of Community and Family Medicine, Howard University College of Medicine, USA

7Department of Medicine, Howard University School of Medicine, USA

8Department of Surgery, Georgetown University College of Medicine, USA

9Department of Orthopedic Surgery, Northwestern University College of Medicine, USA

Abstract

Blacks have a greater need for kidney transplants than other American ethnic groups. Overrepresented on kidney transplant waiting lists (13%), they account for 35% of those waiting. Recent studies show that Black live donors are at greater risk for kidney failure, (44%) after donation, compared to other ethnicities. Explanations for these live donation data are few. While diabetic, hypertensive or morbidly obese Blacks are excluded as live donors; those overweight or obese are not.

Objective

To examine relationships between BMI, waist circumference [WC] and GFR as potential risk factors for CKD in relatively healthy Blacks.

Methods

Participants included 214 Black community volunteers from the Washington, DC area. Physical exams, laboratory and anthropometric data were collected. Creatinine clearance (Cr Cl) was calculated using the Cockcroft-Gault equation method.

Results

Sample mean age was 45 years; 48% were males. Mean BMI and waist circumference were 31 and 38 respectively. Bivariate correlation analyses showed BMI and waist circumference correlated with GFR > 130 cc/min. (r = 0.67, p < 0.01 and r = 0.66, p < 0.01, respectively). Logistic regression analyses revealed that BMI and WC classified obese males were more likely to have a GFR > 130. BMI-categorized obese women were more likely to have a GFR > 130.

Conclusions

Results indicate that increased BMI (> 30 kg/m2), increased waist circumference (> 40 inches) and increased GFR (> 130 ml/min) were strongly correlated in Black volunteers. Black donors with obesity risk factors, when combined with GFR > 130 may be the factors placing overweight or obese AAs at increased risk for CKD after kidney donation.