Table 2: Cut-off value and diagnostic accuracy of urinary VCAM-1, KIM-1, and ET-1 in diagnosing LN.
Urinary Markers | Cut-off value |
Specificity (%) |
Sensitivity (%) |
PPV (%) |
NPV (%) |
VCAM-1 (ng/mg Cr) |
3.6 |
71.7 |
66.7 |
69.3 |
46.7 |
KIM-1 (ng/mg Cr) |
0.14 |
65.0 |
56.7 |
63.9 |
50.6 |
ET-1 (pg/mg Cr) |
1.9 |
96.7 |
80.0 |
92.3 |
90.0 |
Abbreviations: Cr = Creatinine; PPV= Positive Predictive Value; NPV = Negative Predictive Value.