Open Access DOI:10.23937/2572-3286.1510084
Complement-Mediated Hemolytic Uremic Syndrome: Management Challenge behind the Diagnosis - A Case Report
Ana Carlota Vida* , João Carvão, Pedro Vieira, Luís Resende and Gil Silva
Article Type: Case Report | First Published: March 09, 2023
Acute thrombotic microangiopathies (TMA) represent an heterogeneous group of diseases, including complement- mediated hemolytic uremic syndrome (CM-HUS). CM- HUS results from an alternative complement pathway dysregulation as a result of mutations in complement factors or antibodies against these factors. It is important to exclude secondary causes of TMA before establish CM- HUS as a final diagnosis. However, this may be challenging, since complementary evaluation is not always immediately ...
Open Access DOI:10.23937/2572-3286.1510083
Muco-Cutaneous Manifestations in 144 Renal Transplant Recipients: A Single Center Analysis
Najoua Ammar, Mariam Meziane, Nadia Ismaili, Leila Benzekri and Karima Senouci
Article Type: Case Series | First Published: March 05, 2023
Renal transplantation is the best treatment for the replacement of renal function. The majority of dermatological complications related to renal failure regress after transplantation. Nevertheless, the chronic and powerful systemic immunosuppression, gave rise to a series of mucocutaneous manifestations, hence the need for a systematic and regular follow-up in dermatology. The aim of our work was to evaluate the frequency and the clinical spectrum of dermatological complications observed in rena...
Open Access DOI:10.23937/2572-3286.1510082
Renal Angina Index and Neutrophil-to-Lymphocyte Ratio: Predictive of Acute Kidney Injury in PICU
Peerapohn Pongsupamongkol, MD, Rujipat Samransamruajkit, MD and Tawatchai Deekajorndech, MD
Article Type: Original Article | First Published: January 23, 2023
Acute kidney injury (AKI) is associated with increased mortality in pediatric intensive care unit (PICU) patients. Early detection of AKI helps clinicians to manage promptly. Renal angina index (RAI) is established from changes in serum creatinine and condition of patients. Neutrophil-to-lymphocyte ratio (NLR) is calculated from a complete blood count (CBC). There are very few studies on the application of RAI and NLR in PICU. This study aims to evaluate the efficacy of RAI and NLR as AKI biomar...
Open Access DOI:10.23937/2572-3286.1510080
Morphological Changes of the Kidney in Patients with COVID-19
Article Type: Review Article | First Published: November 03, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-COV2) is a single stranded RNA virus and is the cause of the ongoing COVID-19 pandemic and although its main targets are the immune and respiratory systems, acute kidney injury (AKI) has been observed in a high percentage of cases. This is a syndrome which manifests morphologically with the hallmark being acute tubular injury/necrosis and also clinically with the appearing of proteinuria, hematuria, etc. However, this document will focus more...
Open Access DOI:10.23937/2572-3286.1510078
Non Proteinuric Diabetic Kidney Disease: A Narrative Review
Article Type: Brief Report | First Published: September 16, 2022
Albuminuria followed by a decline in glomerular filtration rate has been described to be the classical phenotype of diabetic kidney disease (DKD). A new phenotype, non albuminuric diabetic kidney disease (NADKD), has recently been observed in patients with decreased renal function and a urine albumin excretion rate < 30 mg in 24 hours or a urine albumin creatinine ratio of < 30 mg/g....
Open Access DOI:10.23937/2572-3286.1510076
Increased Hemodialysis Sessions during Pregnancy Improve Fetal Development and Reduce Mortality: Literature Review
Raiani Feu Cassandro, Mirela Dias Gonçalves and Filipe Martinuzo Filetti
Article Type: Original Article | First Published: August 22, 2022
Renal failure is a chronic disease of complex treatment and has a great impact on people’s quality of life. Pregnancy in women on renal replacement therapy is considered high risk, requiring specific care to promote adequate treatment and improvement in maternal and fetal outcomes. This study consists in evidencing the effects of the increase of hemodialysis sessions on the health of pregnant women with Chronic Renal Insufficiency....
Open Access DOI:10.23937/2572-3286.1510075
Urinary Tract Infections in Patients with Solid Tumors: Retrospective Study
Souhir Khemiri, Sonda Masmoudi, Sonda Mezghanni, Wala Ben Kridis, Adnene Hammami and Afef Khanfir
Article Type: Original Article | First Published: July 28, 2022
Urinary tract infection (UTI) is one of the most common infections in patients with cancer. It may occur at different phases of the disease and results from the interaction of several factors. The objective of our study was to determinate the particularities of these infection in this special population....
Open Access DOI:10.23937/2572-3286.1510074
Renal Involvement following Snake Bite Envenomation
Haider Omer and Abdulmalik Alhomrany
Article Type: Research Article | First Published: July 28, 2022
This study aimed to determine the frequency of renal involvement following snake envenomation and the risk factors that contribute to the development of such complications. This retrospective study was carried out at Asir Central Hospital, a tertiary and referral hospital located in the southern part of Saudi Arabia....
Open Access DOI:10.23937/2572-3286.1510073
Pathomorphology of Kidney Damage in Covid-19: Possible Etiological Factors
Rostislav Axenciuc, MD, Igor Sai, MD, Anatoliy Bondarenko, MD, Vasyl Kopcha, MD, and Kateryna Metersky, PhD
Article Type: Original Article | First Published: July 13, 2022
The study aim was to study the histological picture of damaged kidneys in patients who died from COVID-19, as well as to attempt to find the objective causes of renal pathology at COVID-19. Kidney damage in this disease is still considered mainly secondary and associated with multiple organ failure, hypoxia, ischemia, disseminated intravascular coagulation (DIC) at severe and extremely severe disease....
Open Access DOI:10.23937/2572-3286.1510072
Thyroid-Stimulating Hormone and Estimated Glomerular Filtration Rate
Sameena Iqbal, Barama Dalila, Davine Yang, Khashayar Rafat Zand and Celena Scheede Bergdahl
Article Type: Original Article | First Published: June 05, 2022
Hypothyroidism has been identified as a comorbidity related to chronic kidney disease (CKD). The retrospective study investigated thyroid function and CKD and assessed the relationship between TSH and urine albumin/creatinine ratio (ACR), the slope of estimated glomerular filtration rate (eGFR), stratified by CKD grades....
Open Access DOI:10.23937/2572-3286.1510071
Ambulatory Blood Pressure Monitoring in Children with Solitary Kidney
Kanjaporn Sirisomboonlarp, Ankanee Chanakul and Tawatchai Deekajorndech
Article Type: Original Article | First Published: May 11, 2022
Children with a solitary kidney are at risk of developing hypertension due to decreased nephron number with a consequence of hyperfiltration of the remnant. In patients with high-risk conditions, ambulatory blood pressure monitoring (ABPM), which records blood pressure (BP) for 24 hours, is helpful in detecting hypertension. To investigate the prevalence of hypertension in children with solitary kidney using 24-h ABPM and comparing with the office blood pressure (OBP). Twenty-three patients age...
Open Access DOI:10.23937/2572-3286.1510070
Cocaine Induced ANCA Negative Vasculitis - A Diagnostic Dilemma!
Kunal Bhuta, Kriti Devkota2 and Haris Mobeen
Article Type: Case Series | First Published: April 24, 2022
Cocaine is an addictive stimulant drug. In 2014, about 913,000 Americans met the Diagnostic and Statistical Manual of Mental Disorders criteria for dependence or abuse of cocaine. Approximately 69% of Cocaine has been contaminated with Levamisole. Levamisole has been found to be immunogenic causing anti-neutrophil cyto-plasmic antibody (ANCA)-associated cutaneous vasculitis in 88-100% patients. 24-year-old male with a history of polysubstance abuse including IV drug abuse presented with complain...
Open Access DOI:10.23937/2572-3286.1510069
Safety and Efficacy of Patiromer in Kidney and Liver Transplant Recipients
Abigail M Servais, PharmD, Eric D Langewisch, MD, Scott G Westphal, MD, and Clifford D Miles, MD
Article Type: Brief Report | First Published: March 17, 2022
Kidney transplant recipients (KTR) and liver transplant recipients (LTR) are at risk for elevation in serum potassium post-transplant. Patiromer is approved by the Food and Drug Administration for the treatment of hyperkalemia, but there is limited safety and efficacy data for its use in solid organ transplantation. We retrospectively reviewed adult KTR and/or LTR transplanted between October 2015 and September 2019 treated with patiromer. 17 KTR, 13 LTR, and 2 simultaneous liverkidney recipient...