Review Timeline | CrossMark Policy | ClinMed Features
logo
International Journal of

Diabetes and Clinical ResearchISSN: 2377-3634

Archive

 Open Access DOI:10.23937/2377-3634/1410055

The Burden of Co-morbid Depression in Ambulatory Patients with Type 2 Diabetes Mellitus at Kenyatta National Hospital, Kenya

Kanu Joseph E, Otieno CF Frederick, Karari Emma M, Okech-Helu Violet and Mutai Kenn

Article Type: Research Article | Indexed Archive: Volume 3

This was a cross-sectional study done on patients living with type-2 diabetes on follow-up at the diabetes out-patient clinic (DOPC) at the KNH. Systematic sampling method was used to recruit 220 study subjects. The PHQ-9 questionnaire was used to assess for co-morbid depression. Socio-demographic and clinical details were obtained both from the subjects and their medical records. Physical examination was done, including blood pressure and BMI determined. Blood samples were collected from the cu...

 Open Access DOI:10.23937/2377-3634/1410054

High Glycaemic Variability is Associated with Worse Diabetes-related Well-being in Type 2 Diabetes Patients on Insulin Therapy, an Observational Study

W L de Ranitz-Greven, D H Biesma, B Silvius, M Bons, H W de Valk and J W J Beulens

Article Type: Research Article | Indexed Archive: Volume 3

This cross-sectional observational study was conducted at the University Medical Centre Utrecht (UMCU), the Netherlands (February 2010-July 2013). Type 2 diabetes patients attending the (outpatient) clinic of the UMCU were approached to participate in a nationwide biobank study. In the UMCU, patients were also approached to participate in a local add-on study (this study), which required separate consent....

 Open Access DOI:10.23937/2377-3634/1410053

African-origin Mitochondrial DNA Variants as a Contributing Factor to Susceptibilities for Diabetes and Age-related Diseases

Kenney MC, Falatoonzadeh P, Atilano SR, Chwa M, Caceres-del-Carpio J, Malik D, Boyer DS, Nesburn AB and Kuppermann BD

Article Type: Research Article | Indexed Archive: Volume 3

African-origin populations are more susceptible to diabetes and other age-related diseases compared to European-origin populations, but mechanisms for the differential susceptibility remain unknown. Human mitochondrial (mt) DNA haplogroups are maternally inherited ancient polymorphisms representing different geographic origins of populations. Haplogroups are defined by accumulations of single nucleotide polymorphisms (SNPs), some of which cause changes in amino acids and rates of mtDNA replicati...

 Open Access DOI:10.23937/2377-3634/1410052

Association of Uncontrolled Glycemia with Periodontal, Urinary Tract and Cervical Vaginal Infections in a Group of Type 2 Diabetic Women during Pregnancy and during the Postnatal Period

Rosa Maria Diaz-Romero, Gerardo Casanova-Roman, and Manuel Salvador Robles-Andrade

Article Type: Research Article | Indexed Archive: Volume 3

To determine whether periodontal infections (PI), urinary tract infections (UTI) and cervical vaginal infections (CVI) are associated with the incidence of uncontrolled glycemia (UCG) in type 2 diabetics in the third trimester of their pregnancy and during the postnatal period. An observational, prospective, longitudinal, comparative study was carried out. Patient selection was carried out through consecutive non-probability sampling....

 Open Access DOI:10.23937/2377-3634/1410051

Quantitative Models for Evaluating the Correlation between Baseline Hba1c Levels and Sitagliptin as Monotherapy or Dual Therapy Treatment in Type 2 Diabetes: A Meta-Regression Analysis

Jiajing Yin, Yi Lin, Mingyu Gu and Yongde Peng

Article Type: Research Article | Indexed Archive: Volume 3

Baseline glycated hemoglobin (HbA1c) is critical in assessing anti-diabetic agent efficacy due to its ability to alter the response of HbA1c reduction to dipeptidyl peptidase-IV (DPP-IV) inhibitors. With meta-regression, we aim to investigate the quantitative relationship between baseline HbA1c levels and HbA1c reduction in response to sitagliptin as a monotherapy or metformin + sitagliptin as dual therapy. Additionally, we intend to study the slope difference between monotherapy and dual therap...

Volume 3
Issue 1