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Case Report  |   Volume 2, Issue 2

Idiopathic Granulomatous Mastitis - A Great Mimic

Akash Virupakshaiah, Praneeth Pasam, Prachi Kala, Shilpa Lakkundi and Mayilvaganan Sabaretnam
Abstract

Idiopathic Granulomatous Mastitis (IGM) is an uncommon breast disease often mistaken for breast infection, abscess or Carcinoma. Here are two cases of IGM diagnosed after prolonged ineffective treatment of presumed infectious mastitis with abscess and carcinoma. The diagnosis was confirmed by biopsy and the patients were further evaluated to exclude other causes that would present with granulomatous formation.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410019

Opinion  |   Volume 2, Issue 2

Can Genetic Testing Provide Information to Develop Customized Nutrigenomic Solutions for Reward Deficiency Syndrome?

Kenneth Blum, Rajendra D Badgaiyan, Zsolt Demotrovics, James Fratantonio, Gozde Agan and Marcelo Febo
Abstract

We are entering the era of genomic medicine and neuroimaging as it relates to addiction a subset of Reward Deficiency Syndrome. In 2005 our laboratory received the first USA patent on Nutrigenomics and RDS treatment. This was awarded on the basis of our earlier work showing anti-addiction activity of a nutraceutical consisting of amino-acid precursors and enkephalinase inhibition properties and our discovery of the first polymorphic gene (Dopamine D2 Receptor Gene [DRD2] to associate with sever alcoholism.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410018

Case Report  |   Volume 2, Issue 2

A Case of Hematogenous Spread of E. coli causing Clinical Chorioamnionitis

Anne Kennard, Michael R. Foley and Jordan Perlow
Abstract

This case report details a case of chorioamnionitis via hematogenous spread of bacteria following a perforation of the small bowel. Chorioamnionitis is typically thought of as an ascending infection so this case serves as a reminder that intraamniotic infection can arise from multiple sources including bacteremia. The signs and symptoms may be the same as a typical intraamniotic infection, however, may require different treatment due to the different route and pathogens associated with hematogenous spread.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410017

Review Article  |   Volume 2, Issue 2

Outcomes of Influence of Dimethylarginine Derivats, PAD Isoenzymes, or both as Hallmark on Citrullinisation Process on Autoantigens ACPA/ Anti CCP Antibodies overall for Diagnosis in Rheumatoid Arthritis

Dejan Spasovski and Tatjana Sotirova
Abstract

When establishing new diagnostic method for detection of the endothelial dysfunction in Rheumathoid Arthritis (RA), it is necessary to compare the diagnostic values with other laboratory variables. Aim: To Assess Asymmetric Dimethylarginine (ADMA) in RA and study its relation to ACPA and different clinical and laboratory parameters of disease activity in early non treated RA patients.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410016