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Case Report  |   Volume 2, Issue 3

Metastatic Gallbladder Cancer Masquerading as Primary Colon Malignancy

Zhifei Sun, Jonathan Galeotti, Shannon McCall and Christopher R. Mantyh
Abstract

We report a 69-year-old female with personal history of gallbladder cancer who was referred to our institution with a circumferential obstructing intra-luminal colonic mass that possessed pathological features common to both primary colorectal as well as gallbladder cancer, which posed a significant diagnostic and treatment challenge. This case reviews the method and rationale for arriving at the final diagnosis of gallbladder cancer metastasis and highlights the importance of modern molecular diagnostics as well as close communication between the pathologist and surgeon in its process.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410024

Research Article  |   Volume 2, Issue 3

Experimental Use of Transcranial Magnetic Stimulation (TMS) to Treat Tinnitus in a Deaf Patient

Sarah M. Theodoroff and Robert L. Folmer
Abstract

A 28-year-old deaf female patient underwent 10 sessions of repetitive Transcranial Magnetic Stimulation (rTMS) as a participant in a placebo-controlled clinical trial for treatment of tinnitus. Trial participants received 2000 pulses of rTMS per session at a stimulation rate of 1 Hz. The neural target for rTMS was auditory cortex within Heschl's gyrus. The primary outcome measure was the Tinnitus Functional Index (TFI); secondary outcome measures included a Visual Numeric Scale (VNS) for selfrated tinnitus loudness, Beck Depression Inventory II (BDI-II) and State Anxiety Inventory (SAI).

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410023

Research Article  |   Volume 2, Issue 3

Effect of Cardiac Resynchronization Therapy on Left Ventricular Diastolic Function

Kammoun Ikram, Marrakchi Sonia, Jebri Faten and Kachboura Salem
Abstract

Cardiac Resynchronization Therapy (CRT) improves systolic performance in Heart Failure (HF). However, the effects of CRT on Left Ventricular (LV) diastolic function were variable and not fully understood. The aim of this study was to determine the effects of cardiac resynchronization therapy on LV diastolic filing pattern and the relation between the diastolic filing pattern and the response to CRT.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410022

Case Report  |   Volume 2, Issue 3

Ocular Lyme Disease Simulating Acute Posterior Multifocal Placoid Pigment Epitheliopathy

Mingwu Wang, Rahul N. Khurana, Jill J. Hopkins and Narsing A. Rao
Abstract

A 27-year old man presented with ocular symptoms and signs of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) who was also confirmed to have acute Lyme Disease (LD) by serology. The patient was treated timely for systemic LD and the APMPPE-like ocular findings regressed. Possible mechanism linking APMPPE and LD was discussed in conjunction with acute syphilitic posterior placoid choroiditis, another spirochete infection.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410021

Case Report  |   Volume 2, Issue 3

Combined Lensectomy with Vitrectomy for Secondary Glaucoma and Traumatic Iridocyclitis after Ocular Blunt Trauma

Wei Xu, Zheng Wang and Ao Rong
Abstract

Traditional trabeculectomy has been the main surgery for many kinds of glaucoma. However, it is of limitation and high risk in some cases. Vitrectomy is a significant microsurgery developed in the early 1970s. Anterior segment laceration and traumatic cataract is one of indications of vitrectomy. Besides, malignant glaucoma, soft cataract, crystal located of the anterior chamber and vitreous cornea contact syndrome are also the adaptation disease.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410020