Open Access DOI:10.23937/2378-3656/1410024
Metastatic Gallbladder Cancer Masquerading as Primary Colon Malignancy
Zhifei Sun, Jonathan Galeotti, Shannon McCall and Christopher R. Mantyh
Article Type: Case Report | First Published: March 28, 2015
We report a 69-year-old female with personal history of gallbladder cancer who was referred to our institution with a circumferential obstructing intra-luminal colonic mass that possessed pathological features common to both primary colorectal as well as gallbladder cancer, which posed a significant diagnostic and treatment challenge. This case reviews the method and rationale for arriving at the final diagnosis of gallbladder cancer metastasis and highlights the importance of modern molecular d...
Open Access DOI:10.23937/2378-3656/1410023
Experimental Use of Transcranial Magnetic Stimulation (TMS) to Treat Tinnitus in a Deaf Patient
Sarah M. Theodoroff and Robert L. Folmer
Article Type: Research Article | First Published: March 24, 2015
A 28-year-old deaf female patient underwent 10 sessions of repetitive Transcranial Magnetic Stimulation (rTMS) as a participant in a placebo-controlled clinical trial for treatment of tinnitus. Trial participants received 2000 pulses of rTMS per session at a stimulation rate of 1 Hz. The neural target for rTMS was auditory cortex within Heschl's gyrus. The primary outcome measure was the Tinnitus Functional Index (TFI); secondary outcome measures included a Visual Numeric Scale (VNS) for selfrat...
Open Access DOI:10.23937/2378-3656/1410022
Effect of Cardiac Resynchronization Therapy on Left Ventricular Diastolic Function
Kammoun Ikram, Marrakchi Sonia, Jebri Faten and Kachboura Salem
Article Type: Research Article | First Published: March 23, 2015
Cardiac Resynchronization Therapy (CRT) improves systolic performance in Heart Failure (HF). However, the effects of CRT on Left Ventricular (LV) diastolic function were variable and not fully understood. The aim of this study was to determine the effects of cardiac resynchronization therapy on LV diastolic filing pattern and the relation between the diastolic filing pattern and the response to CRT....
Open Access DOI:10.23937/2378-3656/1410021
Ocular Lyme Disease Simulating Acute Posterior Multifocal Placoid Pigment Epitheliopathy
Mingwu Wang, Rahul N. Khurana, Jill J. Hopkins and Narsing A. Rao
Article Type: Case Report | First Published: March 12, 2015
A 27-year old man presented with ocular symptoms and signs of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) who was also confirmed to have acute Lyme Disease (LD) by serology. The patient was treated timely for systemic LD and the APMPPE-like ocular findings regressed. Possible mechanism linking APMPPE and LD was discussed in conjunction with acute syphilitic posterior placoid choroiditis, another spirochete infection....
