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Research Article Open Access

Some Diagnostic Aspect on Abnormal Nitric Oxide Metabolism and Some Pharmacological Aspects of the most used Drugs in Rheumatoid Arthritis

Dejan Spasovski
Clin Med Rev Case Rep Volume 2, Issue 7

Abstract: Introduction: To evaluate the diagnostic test for Assymetric Dimethyl Arginine (ADMA), Rheumatoid factor (RF), C-reactive protein (CRP), Disease Activity Score with 28 joint ( DAS 28 index ), and to define the effect of untreated rheumatoid arthritis on endothelial function. In order to determine whether ADMA changes depending on the disease evolution, ADMA was used as an indicator for endothelial dysfunction in subclinical atherosclerosis Methods: Using a ELISA technology of DLD-Diagnostika-GMBH for detection of ADMA, the samples of serum and urine have been examined in 70 participants (35 RA who were not treated, 35 healthy controls). RF was defied with the test for agglutination (Latex RF test) in the same participants.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410046

Case Report Open Access

Chorioretinitis as a Rare Presentation of Cat Scratch Disease: A Case Report

Zimmermann, Nicolas Lefebvre, Jaulhac B and Sauer A
Clin Med Rev Case Rep Volume 2, Issue 7

Abstract: A 12-year-old female was referred in our center for management of a chorioretinopathy. Ophthalmologic examination revealed unilateral chorioretinal scar with subretinal detachment. Laboratory evaluation revealed IgG antibodies for Bartonella hensalae. Treatment with oral azithromycin led to regression of lesions, resolution of subretinal detachment, and improvement in visual acuity.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410045

Case Report Open Access

Potentiating the Adverse Effects of Zolpidem in a Patient with Alcohol Dependence and SSRI use

Nitin Chopra, Abner Rayapati and Aarti Patel
Clin Med Rev Case Rep Volume 2, Issue 7

Abstract: Though rare, zolpidem has been implicated in perceptual disturbances. Zolpidem elimination can be reduced with liver or kidney pathology. Concomitant Selective Serotonin Reuptake Inhibitor (SSRI) and alcohol use have increased susceptibility to delirium. This case describes a 63 year old Caucasian male, seen by the consulting service, having depression and alcohol dependence, presenting with auditory and visual hallucinations with paranoid delusions. He was prescribed zolpidem 10mg for several years, but reported doubling his dose recently, until stopping the medication 7 days prior to hospitalization. He was non-compliant with citalopram 40mg daily.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410044

Research Article Open Access

Left Atrial Versus Biatrial Maze Procedures in Atrial Fibrillation: Initial Institutional Randomized Trial with Literature Overview

Walid Ben Ali, Pierre Page, Jean Lambert, Michel Carrier and Denis Bouchard
Clin Med Rev Case Rep Volume 2, Issue 7

Abstract: The objective of study is to compare in a randomized fashion biatrial and left atrial Maze by continuous event recorder at one year follow-up. Methods: From January 2011 to December 2012, 19 patients were prospectively enrolled. Patients were allocated in 3 groups regarding their rythm, 7 continuous atrial fibrillation, 8 paroxysmal atrial fibrillation and 4 sinus rhythm with atrial size above 45 mm. Patients were randomized to receive left atrial or biatrial or not receive a Maze. Patients were followed prospectively for 1 year. The interrogation of the recorder was done at 6 and 12 months.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410043

Case Report Open Access

An Unusual Foreign Body in the Neck: A Case of Sternal Wire Migration

O'Connell BP, DeNino WF and O'Rourke AK
Clin Med Rev Case Rep Volume 2, Issue 7

Abstract: Migration of sternal wires is a rare, but potentially serious, complication of median sternotomy and there are a limited number of reports in the literature regarding such migration. Most of these reports document cardiac and/or vascular injuries related to thoracic migration of stainless steel wires. Imran et al. reported bilateral pneumothoraces due to lateral displacement of sternal wires. Rungatscher et al. described sternal wire segments adjacent to, and inside of, the sternal insertion of the sternocleidomastoid muscle resulting in an intramuscular hematoma, but the wire itself had not migrated into the cervical region.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410042

Volume 2
Issue 7