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Case Report  |   Volume 3, Issue 12

Dapagliflozin- Induced Severe Ketoacidosis Requiring Hemodialysis

Ossama Maadarani, Zouheir Bitar and Rashed Alhamdan
Abstract

The availability of novel classes of medication for the treatment of type 2 Diabetes mellitus (type 2 DM) provides doctors with options to choose individualized treatments based on patient and agent characteristics beyond metformin therapy, as per current guidelines. Independent of impaired beta-cell function and insulin resistance, sodium glucose cotransporter type 2 (SGLT2) inhibitors represent a different treatment strategy for reducing plasma glucose levels and glycosylated hemoglobin concentrations by increasing urinary glucose excretion through reduced renal glucose reabsorption.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410150

Case Report  |   Volume 3, Issue 12

Isolated Limb Infusion in a Pregnant Patient with Sarcoma of the Upper Extremity: A Case Report with Literature Review

Milovanov V, Wodago FM, Sittig M and Gushchin V
Abstract

Several scientific publications have shown Isolated Limb Infusion (ILI) as a promising treatment option for patients with soft tissue sarcomas. This minimally invasive technique has a high complete response rate (42-90%) and could serve as a neo-adjuvant treatment for limb sparing sarcoma surgical treatment to increase the likelihood of R0 resection. ILI technique has low levels of systemic leak (< 1%) and systemic toxicity rate, which makes this treatment potentially relevant in pregnant patients when radiation therapy is not an option.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410149

Case Report  |   Volume 3, Issue 12

An İncidental Findings of Polysplenia Syndrome in an Adult Patient with Multiple Anomalies

Mehmet Sedat Durmaz, Ali Cengiz, Serdar Arslan, Hasan Erdogan, Ismet Tolu and Arzu Cengiz
Abstract

Polysplenia syndrome is a rare congenital subtype of heterotaxy syndrome associated with various visceral and vasculer anomalies. Polysplenia syndrome is characterized by presence of two or more spleens and anomalies of other asymetric organs. It is reported incidence of 1 per 250.000 and more common in females. Here, we report the case of a 53-year-old woman who presented with polysplenia syndrome.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410148

Case Report  |   Volume 3, Issue 12

The Use of Macitentan in the Treatment of Out-of-Proportion Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease: Case Report

Luca Fallavollita, Paolo Spinaci and Pietro Scendoni
Abstract

Pulmonary hypertension (PH) is an important complication of chronic pulmonary disease, especially of chronic obstructive lung disease (COPD). The exact prevalence of PH in COPD is unknown. PH is defined as an increase in mean pulmonary arterial pressure (PAPm) > 25 mmHg at rest as assessed by right heart catheterization. In most cases, PH in COPD patients is usually mild to moderate. Only a small proportion of this cohort may present with severe pulmonary hypertension.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410147

Case Report  |   Volume 3, Issue 12

A Case of Pyonephrosis of an Obstructed Atrophic Kidney

Fareeha Khan, Rasha Nakhleh and Theodore Suh
Abstract

This case is of a 67-year-old male who presented to the office with multiple symptoms and was treated for a variety of infections before the correct diagnosis of pyonephrosis in the setting of chronic ureteropelvic junction (UPJ) obstruction was made.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410146

Review Article  |   Volume 3, Issue 12

Outcome of Some of the Many Aedes Albopictus (Skuse, 1895) Mosquito Encounters with Man

Daniel Benharroch and Yane-Bianca Benharroch
Abstract

Aedes albopictus, the Asian tiger mosquito, has lately become prominent, globally, while showing a marked "migratory" capacity. We have scrutinized the many consequences of the encounters between the Asian tiger mosquito and humans, and have chosen to review several of them. It seems inevitable that this mosquito be more and more present in our lives. It is a tremendous nuisance to man through its bite. However, several arboviral infections are the main consequences of these confrontations, encompassing all ranges of severity. Few means of prevention, however, have proven successful.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410145

Case Report  |   Volume 3, Issue 12

Adult Rasmussen's Encephalitis

Campanille Veronica, De Aguirre Ines, Crespo Jose, Gonzalez Macarena, Lopez Juan Ignacio, Lucero Carolina, Perez Garcia Jorgelina and Knorre Eduardo
Abstract

Rasmussen's Encephalitis (RE) is defined by the presence of partial seizures associated to focal progressive cortical atrophy and in advanced stages hemiparesis, hemianopia and cognitive impairment, though it may appear focal neurological deficits at onset; and it's more prevalent in childhood. Approximately, 10% presents at adulthood. Because of its immunologic physiopathology, RE is considered autoimmune epilepsy. Treatment is focused on antiepileptic drugs (AEDs), steroids, intravenous immunoglobulins (IVIg) and immunosuppressant drugs.

PDF   |    Full Text | DOI: 10.23937/2378-3656/1410144


Volume 3
Issue 12