Clinical Medical

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Case Report Open Access

Pulmonary Lymphangitic Carcinomatosis due to Metastatic Adenocarcinoma of the Lung: A Case Report

Somaya AM Albhaisi and Neama Luqman
Clin Med Rev Case Rep Volume 3, Issue 3

Abstract: Pulmonary lymphangitic carcinomatosis (PLC) is part of the spectrum of metastatic disease. Most cases result from dissemination of adenocarcinomas. Micro hematogenous spread to the periphery of the lung, with subsequent retrograde, centripetal lymphatic extension toward the hilar region, is the responsible mechanism in approximately 75% of patients. The remaining cases are due to retrograde extension from a hilar tumor or from an ipsilateral lung or breast carcinoma. In the latter settings, the lymphangitic spread is unilateral; in comparison, micro hematogenous seeding is frequently bilateral. HRCT can detect lymphangitic tumor in up to 50% of patients who are symptomatic but have normal appearing lungs on chest radiography. The imaging features of lymphangitic tumor are determined by the pattern of bronchovascular and lymphatic spread.

PDF   | Full Text  DOI: 10.23937/2378-3656/1410099

Case Report Open Access

Topical Cream Curadermbec5 Treats a Recalcitrant Basal Cell Carcinoma

Batsev AF, Dobrokhotova VZ and Cham BE
Clin Med Rev Case Rep Volume 3, Issue 3

Abstract: Solasodine rhamnosides, solamargine and solasonine, are antineoplastics with high affinity, high efficacy and low toxicity as shown in cell culture, animal and human studies. The mode of action is by apoptosis and is accompanied by a high order of specificity. This specificity towards cancer cells is ideal for treating skin cancers. Previous studies show that solasodine rhamnosides in a topical cream formulation CuradermBEC5 is a highly regarded therapy for nonmelanoma skin cancers.

PDF   | Full Text  DOI: 10.23937/2378-3656/1410098

Short Note Open Access

Prevention, Detection and Diagnosis of Expressive Oral Language Disorders in Premature Infants

Charollais Aude
Clin Med Rev Case Rep Volume 3, Issue 3

Abstract: To prevent language disorders in a vulnerable population we must understand that the language development is a multisensory and above-modal integration with specific neurodevelopmental period, some of which remain to study. The oral language development is done according to time of neuro developmental time for which information was recently confirmed in children born preterm.

PDF   | Full Text  DOI: 10.23937/2378-3656/1410097

Case Report Open Access

Spontaneous Spleen Rupture: An Unusual Involvement of the Spleen in Systemic Lupus Erythematosus

Maria do Socorro Teixeira Moreira Almeida, Amanda Gualberto Carvalho, Lina Gomes dos Santos, Eliton Carlos Batista de Sousa and Gabriela Lustosa Said
Clin Med Rev Case Rep Volume 3, Issue 3

Abstract: The involvement of the reticuloendothelial system in systemic lupus erythematosus (SLE) concomitant to the disease activity is highly variable, and well-recognised but spontaneous splenic rupture is an unusual occurrence. We report a 35-year-old woman with SLE who had spontaneous splenic rupture during the course of her illness. The spleen rupture was evident on histophatological analysis. A brief review of spontaneous splenic rupture in systemic lupus erythematosus (SLE) is also presented.

PDF   | Full Text  DOI: 10.23937/2378-3656/1410096

Case Report Open Access

Socket Reconstruction after Firework Explosion Injury

Reili Rebane, Mari Tamsalu and Artur Klett
Clin Med Rev Case Rep Volume 3, Issue 3

Abstract: We report a challenging case of orbital socket reconstruction. A 49- year-old man presented two weeks after fireworks exploded in his face. He had multiple orbital bone fractures on the right and the globe was enucleated because of severe damage. No primary orbital implant was used due to infection risk. One month after the trauma he suffered from infection of the conjunctival sac and periorbital skin despite initial intravenous and oral antibiotics. Because of inability to wear a cover shell eye prosthesis the socket reconstruction was started ten months after trauma.

PDF   | Full Text  DOI: 10.23937/2378-3656/1410095

Case Report Open Access

Atypical Presentation of Madelung Disease

Maisel Lotan Adi, Retchkiman Meir and Gronovich Yoav
Clin Med Rev Case Rep Volume 3, Issue 3

Abstract: We present a unique case of a sixty two year old woman with symmetric lipomatosis of the lower back, similar to cup C female breast. Lipoma is the most common type of soft tissue mesenchymal tumor. Lipoma is commonly found in the upper back, neck, shoulder and abdomen, and rarely in the face, hands or feet. When lipomatosis is symmetrical it is often termed Multiple Symmetrical Lipomatosis (MSL), also known as Madelung disease, a rare syndrome of unknown etiology.

PDF   | Full Text  DOI: 10.23937/2378-3656/1410094

Volume 3
Issue 3