International Archives of

Internal MedicineISSN: 2643-4466


 Open Access DOI:10.23937/2643-4466/1710036

Association between the Third Trimester Vaginal Microbiome and Time from Full Cervical Dilation to Delivery: An Exploratory Study

Steven S Witkin, Daniel Skupski, Antonio F Moron, Allison Boester, Iara M Linhares and Larry J Forney

Article Type: Research Article | First Published: December 31, 2021

Bacteria from the vagina are transported into the uterus during labor. We evaluated if the vaginal microbiome in the third trimester of pregnancy was related to the length of the second stage of labor. The composition of the vaginal microbiome in 73 women in their third trimester was measured by analysis of the V1-V3 region of the gene coding for bacterial 16S ribosomal RNA. The vaginal concentration of D- and L-lactic acid was determined by ELISA. The time from full dilation to delivery was ob...

 Open Access DOI:10.23937/2643-4466/1710035

Clinical Predictors of In-Hospital Outcomes in COVID-19 Patients: A Retrospective Cohort Study

Maiara A Floriani, MSc, Marina Bessel, ScD, Isabelle W Zorzo, BSHCA, Andressa B Glaeser, BSc, Rafael Domingos Grando, MD, Raphael Goveia Rodeghiero, MD, Mohamed Mutlaq Parrini, BEcon, MPhil, Gisele Nader Bastos, MD, ScD and Luiz Antonio Nasi, MD, ScD

Article Type: Research Article | First Published: December 31, 2021

We do not have detailed evidence on conditions or treatments that act as predictors of hospital outcomes. To identify the clinical predictors of hospital outcomes in COVID-19 patients and to evaluate the effect of therapeutic’s interventions on length of stay, ICU admission, need for mechanical ventilation (MV) and mortality. The primary outcome was to assess whether any treatment alone or in combination with standard care, was able to reduce ICU admission, need for MV or mortality. The second...

 Open Access DOI:10.23937/2643-4466/1710034

Ulcerative Colitis Presenting as an Anal Fissure in 78-Years-Old Woman

Babić Žarko, MD, PhD, Vukelić Marković Mirjana, MD, PhD, Banić Marko, MD, PhD and Medić Barbara, MD

Article Type: Case Report | First Published: September 29, 2021

A number of complications are known to occur in the course of inflammatory bowel diseases. However, perianal fistulas and fissure can occur with or without active inflammatory bowel disease, occurrence of which prior to the development of ulcerative colitis is a rare occasion. Here we report a case of ulcerative colitis, which was misdiagnosed, treated as a perianal fissure and anal pressure ulcer without recognizing inflammatory bowel disease. Inflammmatory bowel diseases (IBDs) are chronic imm...

Volume 5
Issue 2