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International Archives of

Medical MicrobiologyISSN: 2643-4008

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 Open Access DOI:10.23937/iamm-2017/1710007

Physicochemical and Biopharmaceutical Characterization of N-Iodomethyl-N,N-Dimethyl-N-(6,6-1 Diphenylhex-5-En-1-Yl) Ammonium Iodide and A Promising Antileishmania Delivery System

Maritza Fernandez, Luz Amalia Rios-Vasquez, Rogelio Ocampo-Cardona, Oscar Florez, David L Cedeno, Teresa M Garrigues, Antonio J Almeida, Ivan D Velez and Sara M Robledo

Article Type: Research Article | First Published: October 13, 2018

Cutaneous leishmaniasis (CL) is an infectious disease endemic in tropical and subtropical countries. The current drugs have severe drawbacks that restrict their use and enhance the need for better drugs. Recently, the N-iodomethyl-N,N-dimethyl-N-(6,6-diphenylhex-5-en-1-yl) ammonium iodide (C6I) was identified as a promising compound for the topical treatment of CL. The need for oral drugs with potential use to treat cutaneous, mucosal and visceral leishmaniasis, in the present work were determin...

 Open Access DOI:10.23937/IAMM-2017/1710006

Prevalence of Vaginal Infections in Women under Screening to HPV Infection and Cervical Lesions in Brazilian Basic Health Service

Emanuella Francisco Fajardo, Gabriela Roberta Braz, Mara Rosa, Tatiane Marques, Bruno Belmonte Martinelli Gomes, Thiago Mantello Bianco, Ana Karina Marques Salge, Dayana Pousa Siqueira Abrahao, Eduardo Elias Vieira de Carvalho, George Kemil Abdalla and Douglas Reis Abdalla

Article Type: Research Article | First Published: October 06, 2018

Vaginal infections and inflammations are responsible for the most demand at gynaecology, because the main complains are leucorrhea and vulvovaginitis, there is a specifically interest in cervix cancer prevention. The aim of this study is to understand the prevalence of vaginal infections cases and cervical lesions, found in women attended at health basic units from Igarapava, Sao Paulo state, Brazil....

 Open Access DOI:10.23937/IAMM-2017/1710005

Prognostic Factors in Breast Cancer: From Staging to the Immunohistochemical Profile of Patients with Breast Cancer in a Reference Hospital of Ceara - Brazil

Pires Eduardo De Lima Sa, Morais Livia Mota, Pires Amanda De lima Sa, Matsuda Luis Otavio, Matsuda Josie Budag and Alves Angelo Roncalli Melo

Article Type: Research Article | First Published: October 05, 2018

Know the tumor stage of breast cancer and identify the immunohistochemical markers are important in the evaluation of predictive and prognostic factors, in the differential diagnosis of breast lesions and in the determination of the possible origin of metastatic neoplasms, besides helping to define the type of treatment. Cross-sectional and quantitative study of patients diagnosed with breast cancer, submitted to treatment at the Ceara Cancer Institute (ICC) mastology service from 2008 to 2012. ...

 Open Access DOI:10.23937/iamm-2017/1710004

Streptococcus salivarius Meningitis in Immunocompetent: A Case Report

Abdelrahman M Elsawy, Hani S Faidah and Elrashdy M Redwan

Article Type: Case Report | First Published: August 08, 2018

Streptococcus salivarius (S. salivarius) is a rare cause of purulent meningitis. We report a case of meningitis due to S. salivarius in 15-years-old Sudanese boy. Diagnosis was established based on Cerebrospinal fluid (CSF) findings. The patient responded well to systemic antibiotics and recovered completely without any neurological complications after proper supportive measures. In this patient the meningitis caused by S. salivarius was thought to be spontaneous. The importance of bacteriologic...

 Open Access DOI:10.23937/iamm-2017/1710003

Potential of Carcinogenesis Induced by John-Cunningham Virus and Crude-Oil Extracts

Shih-Chao Lin, Christopher Z Lien and Chi-Chen Lin

Article Type: Short Communication | First Published: July 13, 2018

John-Cunningham virus (JCV) has been recognized as a major contributor to progressive multifocal leukoencephalopathy (PML) in humans, especially in immunodeficient patients. While the prevalence rate of PML in human populations could be up to 80%, the occurrence of tumorigenesis is around 0.07%. Thus, we investigated whether crude-oil extracts could synergistically increase the carcinogenesis along with T antigen from JC virus in vitro. Here we analysed the cell cycle distribution and cytotoxici...

 Open Access DOI:10.23937/iamm-2017/1710002

Factors Influencing Adherence to Antiretroviral Therapy among HIV Infected Patients in Nyamagana-Mwanza, Northern Tanzania: A Cross Sectional Study

Samuel Edward Kahema, Maseke Richard Mgabo, Basiliana Emidi, Geofrey Nimrod Sigalla and Debora Charles Kajeguka

Article Type: Research Article | First Published: May 16, 2018

High level of Antiretroviral Therapy adherence among HIV infected patients contributes to better treatments outcome and has additional importance in preventing the development of drug resistance. It also improves the quality of life and makes the patient live longer and healthier. The objective of the study was to determine level of adherence as well as factors influencing adherence to antiretroviral therapy among HIV infected patients in Nyamagana district, Mwanza, Tanzania....

 Open Access DOI:10.23937/iamm-2017/1710001

Potential of Supercritical Solvent Impregnation for Development of Materials with Antibacterial Properties

Irena Zizovic

Article Type: Review Article | First Published: November 20, 2017

Supercritical solvent impregnation is a modern technique which exploits the unique transport properties and qualities of supercritical fluids such as low viscosity, high diffusion coefficients, densities as in a liquid state and zero surface tension, for the fabrication of novel materials. The mentioned properties allow deep penetration of supercritical fluid with a dissolved bioactive substance into a solid matrix enabling even distribution of the active substance through the whole volume of th...

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