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Open Access DOI:10.23937/2643-4008/1710014
Vijay Pancholi
Article Type: Brief Note | First Published: October 25, 2021
Fungal infection caused by Candida auris is now a global crisis. However, its multidrug-resistant nature and onerous identification have left limited therapeutic options resulting in 30-60% mortality. Amphotericin-B (AmB), a broad-spectrum and a potent fungicidal with a rare resistance pattern, is considered a gold-standard antifungal drug. Yet, its antifungal potential is not fully recognized under the pretext of its potential nephrotoxicity. Liposomal AmB formulations are safer than AmB-Deoxyc...
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Open Access DOI:10.23937/2643-4008/1710012
Jayasimha Rao, PhD, Adenike Adenikinju, MD, James M. Gray, MS, Lily Colpitts, MD, Alyson Prorock, BS, Yongde Bao, PhD, Thomas M. Kerkering, MD, Dorothy C. Garner, MD and Roderick V. Jensen, PhD
Article Type: Original Article | First Published: June 17, 2021
Multidrug-resistant (MDR) and virulent pathogenic strains of Pseudomonas aeruginosa (Pa) are among the most dangerous pathogens in healthcare-associated infections. In this study, a comparative analysis was performed on two clinical Pa strains from pneumonia patients, 1) An acute strain (CMC-115) and 2) A chronic multidrug- and carbapenemresistant strain (CMC-097) with distinct phenotypic and genetic characteristics. A transcriptome analysis using both the Pseudomonas DNA GeneChip microarray and...
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Open Access DOI:10.23937/2643-4008/1710011
Abdlmanam Fakron, Idress Hamad Attitalla, Mohamed Younes A Hassan and Sumeet Dwivedi
Article Type: Review Article | First Published: April 30, 2021
Since photosynthesis is the primary process through which light energy absorbed and converted into organic matter, thus, plant chlorophyll pigment (forms A and B) plays an essential role in the progression absorbed solar energy and synthesis of organic matter in a plant. Therefore, this paper aims at the extent to which the optical activity of chlorophyll molecules monitored and methods (non-destructive and destructive) for quantification of chlorophyll content in plants. These methods using to ...
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Volume 3
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Issue 1