International Archives of

Translational MedicineISSN: 2572-4142

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 Open Access DOI:10.23937/2572-4142.1510008

Diagnostic Findings in 60 Cases of Isolated and Syndromic Congenital Olfactory Dysfunction

Jean-Jacques Braun, MD, Marion Renaud, MD, Sebastien Moliere, MD, Vincent Noblet, MD, Stephane Kremer, MD, Helene Dollfus, MD and Sophie Riehm, MD

Article Type: Original Article | First Published: April 15, 2019

Congenital anosmia (CA) is rare comparatively to acquired anosmia. The pathophysiology and the genetic background remain poorly understood. This study aims to review the main clinical and Magnetic Resonance Imaging (MRI) findings to discuss the diagnostic strategy, the pathophysiology and the genetic basis of the different forms of CA. A series of 60 patients with congenital anosmia was reviewed retrospectively out of 425 non-sinus-related anosmia and compared to the literature data. CA was asse...

 Open Access DOI:10.23937/2572-4142.1510007

Investigation of Serum Levels of Leptin, Ghrelin and Growth Hormone in Bahraini Children with Autism

Zuheir Ahmed Hasan, PhD, Ghada Al-Kafaji, PhD, Maryam Isa Al-Sherawi, PhD, Rima Abdul Razzak, PhD, Diab Eltayeb, PhD, Cristina Skrypnk, MD, PhD and Moiz Bakhiet, MD, PhD

Article Type: Original Article | First Published: March 11, 2019

Autism is a complex neurodevelopmental disorder, the pathogenesis of which remains unclear. Recent research suggests a possible role of hormonal abnormalities in the pathogenicity of autism. In this investigation, we measured serum levels of leptin, ghrelin, and growth hormone (GH) in 40 age-matched Bahraini children, 20 with autism (16 males and 4 females) and 20 healthy children (13 males and 7 females). Hormonal levels were measured by enzyme-linked immunosorbent assay method....

Volume 5
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