Oxidative Stress and Cardiovascular Risk: Research Must Persist
Ivan Lozada Martinez, Daniela Torres Llinás, Jaine Anaya Rivera, Jennifer Jiménez Valverde and Milena Castro Berrio
Article Type: Commentary | First Published: December 16, 2020
Advances in medicine and experimental biology have supported the definition of concepts related to the process of cellular stress, depending on new discoveries at the molecular level. Oxidative stress is the product of the activity of various metabolic pathways including the mitochondrial electron chain, Nicotinamide Adenine Dinucleotide Phosphate Oxidase (NADPH), nitric oxide synthase, xanthine oxidase, among others. Physiologically, regular levels of reactive oxygen species (ROS) play a fundam...
Interventional Stroke Treatment in Patients with Tandem Lesions: What Factors Influence the Clinical Outcome?
Elmouden R, Moya A, Reimann G, Adamczewski O, Schwarz M and Rohde S
Article Type: Original Research | First Published: November 05, 2020
Endovascular treatment of acute stroke patients with tandem lesions is technically challenging. We sought to evaluate clinical and interventional factors that might influence the clinical outcome in these patients. We retrospectively analysed the interventional and clinical data of patients with tandem lesions and acute embolic stroke in the anterior circulation that underwent endovascular stroke treatment at our institution. Patients were selected if they had a CTA-proved vessel occlusion of th...
Extensive Tissue Necrosis: A Rare but Catastrophic Complication of Sclerotherapy
Paul Robert Weaver
Article Type: Short Commentary | First Published: March 12, 2020
While sclerotherapy may seem safe, catastrophic complications have been reported, including local and systemic adverse reactions. For example, extensive tissue necrosis and cerebrovascular accident (stroke) Patient selection is vital and treating physicians should be aware of all potential complications and discuss them with their patients, prior to treatment, to obtain informed consent. Physicians also need to be prepared to manage catastrophic complications that could lead to amputation or dea...
Slight Increases of Phosphorus and Sulfur in Human First Septal Perforator Branches of the Left Anterior Descending Artery with Aging
Yoshiyuki Tohno, Setsuko Tohno, Takeshi Minami, Nutcharin Pakdeewong-Ongkana, Noppadol Phasukdee and Pasuk Mahakkanukrauh
Article Type: Original Article | First Published: March 12, 2020
To elucidate age-related changes of the first septal perforator branch (FSB), the authors investigated age-related changes of elements in the FSBs by direct chemical analysis. In addition, the effects of different arterial sizes and genders on element accumulation were investigated in the FSBs. Sixty-two formalin-fixed adult Thai hearts were used and the FSBs were carefully dissected in the hearts. After the arteries were incinerated with nitric acid and perchloric acid, element contents were de...