The Effect of Dexmedetomidine and Propofol on Oxidative Stress Parameters during Lower Extremity Surgery: A Prospective Randomized Trial
Safinaz Karabayirli, Ismail Uras, Cemile Koca, Merve Ergin, Ruveyda Irem Demircioglu, Bunyamin Muslu
Article Type: Original Research Article | First Published: September 12, 2015
Tourniquets are routinely applied during lower extremity surgery in order to reduce bleeding during surgery, provide better surgical conditions and consequently to shorten the duration of the operation. However, an inflammatory response is often activated by tourniquet application, leading to prolonged ischemia and reperfusion; consequently, organ damage such as acute lung injury may occur. Muscular ischemia causes hypoxic cellular changes and anaerobic glycolysis, and its neutrophil activation ...
Safety and Efficacy of Remifentanil for Single Agent Procedural Sedation: A Systematic Review
Jeppe T Jensen, Peter Vilmann, Lars Konge and Moller
Article Type: Review Article | First Published: August 19, 2015
Hospitals and healthcare centers are continuously pushed to deliver a better quality of care with a higher turnover. Hence, there is an increasing demand for shorter procedures and shorter time to discharge. Some of these requirements can be met if sedation is used instead of general anesthesia. Furthermore, sedation, as an alternative to nothing, has its benefits. Two recent studies have shown that sedation for endoscopies increases endoscopist satisfaction, the patient's willingness to undergo...
The Effects of High-Dose Sugammadex on Erythrocyte Deformability in Rats with Renal Failure Generated by Unilateral Ureteral Obstruction
Fusun Bozkirli, Fikriye Dogrul, Faruk Metin Comu, Hande Arpaci, Omer Bayrak, Mustafa Arslan and Yusuf unal
Article Type: Original Article | First Published: August 18, 2015
One of the most common causes of renal insufficiency in children and adults is obstructive nephropathy. Unilateral ureteral obstruction (UUO) is a well-known model to imitate the obstructive nephropathy process in a simple, accelerated and species-independent manner. Previous studies have revealed that morphological lesions in the obstructed kidney are peritubular capillaries rarefaction, tubular atrophy, inflammatory infiltration, widen interstitial space, and progressive tubulointerstitial fib...
Aminophylline does not Prevent Postdural Puncture Headache in Caesarean Section
Ismail Sirit, Ibrahim Ozturk, Dilek Yazicioglu
Article Type: Original Research | First Published: June 20, 2015
We aimed to investigate that whether intraoperative intravenous aminophylline is effective for prevention of postdural puncture headache after caesarean section or not. Materials and method: Records of patients who underwent caesarean section between January, 2013 and November, 2013 with spinal anesthesia were examined retrospectively. Patients older than 18 were included in the study. Failed and conversion to general anesthesia was the exclusion criteria....