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Original Article  |   Volume 3, Issue 3

A New Age for Sepsis/Septic Shock Diagnosis and Management?

Enrico Giustiniano

On April 2014 the New England Journal of Medicine published the results of the trial ProCESS (Protocolized Care for Early Septic Shock): a multi centers study conducted on 1341 patients of 31 academic hospitals of United States. The trial compared three different way to approach and care the septic shock during the first 6 hs.

  PDF   |    Full Text | DOI: 10.23937/2377-4630/3/3/1051

Original Article  |   Volume 3, Issue 3

Which Guidance Method during Tracheotomy Procedure in Patients with Short Neck in the ICU? A Prospective Randomized Study

Esra Ozayar, Handan Gulec, Zehra Baykal Tutal, Munire Babayigit, Mehmet Sirin, Aysun Kurtay and Eyup Horasanli

Percutaneous tracheotomy is a common procedure in the intensive care units (ICU). Although majority of the complications related to this procedure are considered minor, serious complications secondary to tracheotomies are still being reported. Definition of short neck is not clear in the medical literature, but well known to anesthesiologists since they are flagged for possible difficult airway. Thyromental and sternomental distance, range of neck extension and neck circumference are some of the predictors of difficult airway.

  PDF   |    Full Text | DOI: 10.23937/2377-4630/3/3/1050

Research Article  |   Volume 3, Issue 3

Pre-Clinical Pharmacokinetics of Sufentanil-2-Hydroxypropyl-Β-Cyclodextrin Inclusion Complex

Silvana Aparecida Calafatti, Marcelo de Macedo, Juliana Zampoli Boava Papini, Edvaldo Coelho, Cintia Maria Saia Cereda, Jose Pedrazzoli Junior, Eneida de Paula, Daniele Ribeiro de Araujo and Giovana Radomille Tofoli

Opioids are used for the postoperative period, cancer pain and for moderate to severe chronic noncancer pain. Sufentanil (SUF) is a highly lipophilic opioid that presents rapid and highly effective pain relief, but it presents short duration of action. Due to this short duration of action, SUF is currently used as an intravenous anesthetic agent and analgesic adjuvant for surgery and labor.

  PDF   |    Full Text | DOI: 10.23937/2377-4630/3/3/1049