Open Access DOI:10.23937/2469-5866/1510007
Speech Disorder and Behavioral Involvement in a Thalamic Stroke: A Case Report
Paola Caruso, Moretti R and Manganotti P
Article Type: Case Report | First Published: December 14, 2015
Data from literature on clinical manifestation of thalamic strokes have been published for ages. First in 1906 Dejerine e Roussy has spoken about sensory motor disturbances and have opened the door to new pathologic disorders that may occur after thalamic lesions. From 1925 behavior and speech disorders related with thalamic injury were described. Since then a classification of thalamic syndromes into four groups based on the four main arterial territories was accepted. As we know thalamic strok...
Open Access DOI:10.23937/2469-5866/1510005
Guillain-Barre Syndrome with Lymphocytic Pleocytosis of the CSF
Sneha Padidam, Jacqueline Kraft and M Kamran Athar
Article Type: Case Report | First Published: October 8, 2015
60-year-old man presented with progressive lower-extremity weakness that progressed to involve respiratory failure and are flexia over several weeks. Electromyography showed both demyelinating and axonal features. Lumbar puncture revealed a lymphocytic pleocytosis. Given the abnormalities on these tests with a clinical picture of Guillain-Barre the patient underwent extensive paraneoplastic testing and full neuro-axis imaging. Imaging revealed abnormal enhancement of ventral and dorsal nerve roo...
Open Access DOI:10.23937/2469-5866/1510004
Cranial Electrotherapy Stimulation (CES) in Neuropsychiatry: Definition & Insights from Electric Learning Paradigms
Article Type: Research Article | First Published: September 10, 2015
The main point here is that CES method employ at both practices systematic applications of non-invasive, harmless electric currents in the range of 50 micro-to 2 milliamper, varying from 10 Hz to 100 kHz frequencies. They inject from 10 ms to 250 ms by each scalp pair out of an array of EEG electrodes transporting to regions of interest. Such electromagnetic forces induce equivalent number of ionic oscillatory streams crossing the brain in calibrated coulombs. Optimal control regulates by number...
Open Access DOI:10.23937/2469-5866/1510003
Benefits of Temporary Intrathecal Baclofen Therapy: Management of Tone and Spasticity
Melissa Ann Eppinger, Thomas J. Sernas and Catherine Anne Mazzola
Article Type: Case Series | First Published: September 9, 2015
Spasticity and dystonia may develop as a consequence of brain or spinal cord injury (SCI). Central nervous system (CNS) injury may be permanent or temporary, depending on the etiology of brain or spinal cord injury. In anoxic brain injury, there may be transient or reactive demyelination due to cell death or cell dysfunction. If there is ischemia without true infarction, or cell death, there may be some ability of the brain to repair itself or reconstitute the myelination of axons within the whi...
Open Access DOI:10.23937/2469-5866/1510002
MicroRNA in Brain Neoplasia: A Review
Michela Visani, Giorgia Acquaviva, Gianluca Marucci, Moira Ragazzi, Enrico Fraceschi, Alba A Brandes, Giovanni Tallini, Annalisa Pession and Dario de Biase
Article Type: Review Article | First Published: August 27, 2015
MicroRNAs (miRNAs) are small RNAs involved in regulation of several cellular processes and are involved in the silencing of cell's message in a variety of ways. In cancer, miRNAs can be involved in the regulation of important genes involved in tumorigenesis, tumor development, and angiogenesis. For these reasons, miRNAs could have considered oncogenic-miR (miRNA with oncogenic roles) or oncosuppressor-miR (miRNA with tumor suppressor roles). MiRNAs may alter the expression of genes involved in c...
Open Access DOI:10.23937/2469-5866/1510001
External Carotid Artery Steal Syndrome via Occipital-Vertebral Anastomosis
Menarvia Nixon, Anil Nanda and Hugo Cuellar-Saenz
Article Type: Case Report | First Published: August 26, 2015
We describe a case of ECA steal syndrome due to occipital- vertebral anastamosis in an 81 y/o female patient who presented with gait ataxia and dizziness. She was referred to Neuro-interventional Radiology after discovery of carotid bruits on her physical examination. A digital subtraction angiogram confirmed mild internal carotid artery stenosis, however, more concerning was the discovery of retrograde flow of the right vertebral artery with filling of the right external carotid artery via anas...