International Journal of

Brain Disorders and TreatmentISSN: 2469-5866


 Open Access DOI:10.23937/2469-5866/1510021

The Effect of a Functional Intensive Intervention Program on Self-Care in Children with Cerebral Palsy: A Case Study

Rosanne Roelofsma and Eugene Rameckers

Article Type: Original Research | First Published: November 29, 2017

Former studies have shown that usual care in children with Cerebral Palsy (CP) often lacks effectiveness. Task-oriented functional intensive therapies have been shown to be promising for CP patients. The present case study aimed to examine the effect of a task-oriented functional intensive therapy program....

 Open Access DOI:10.23937/2469-5866/1510020

Specific Effects of Antipsychotic Chlorpromazine on Glutamatergic Ionotropic Mechanisms. Novel Targets for Treatment Schizophrenia

Anatoly A Mokrushin

Article Type: Research Article | First Published: October 25, 2017

Chlorpromazine hydrochloride (CPZ) refers to antipsychotic drugs. CPZ is drug of first choice for the treatment of schizophrenia. However, its impact on the main excitatory neurotransmitter system, glutamatergic, is unclear. This issue is the aim of our study....

 Open Access DOI:10.23937/2469-5866/1510019

Microglial NLRP3 Activity in Alzheimer's Disease

Bruno Cabral de Lima Oliveira

Article Type: Review Article | First Published: September 11, 2017

Alzheimer's Disease (AD) is the major disease leading to dementia. This disease is characterized by the presence of β-Amyloid (Aβ) extracellular deposits and neurofibrillary tangles, which induce senile plaques formation. Furthermore, inflammation in AD is mainly mediated by innate immunity-related cells, especially microglia....

 Open Access DOI:10.23937/2469-5866/1510018

Evaluation of Seizures in Patients with Chronic Subdural Hematoma Treated by Burr-Hole Surgery and Risk Factors for Seizures

Tetsuhisa Yamada and Yoshihiro Natori

Article Type: Research Article | First Published: March 27, 2017

Chronic subdural hematoma is one of the most commonly encountered diseases in neurosurgery. The treatment method is well established, but seizures develop as a complication in 2.3% to 20.4% of patients. We studied patients with seizures to clarify the status of patients at the onset of seizures and define risk factors for seizures....

Volume 3
Issue 1