Geographical Variation of Acute Promyelocytic Leukemia: A Single Center Study from Saudi Arabia
Article Type: Brief Report | First Published: December 11, 2022
There is no obvious underlying cause for de novo acute promyelocytic leukemia (APL). Recently two case studies showed that the virus torque teno mini (TTMV) has a role in the pathogenesis of APL/APL-like disease. Few studies reported seasonal or geographical clustering of the disease. As no local published research addressed the effect of these two factors on the incidence of the disease, we aimed to study the relationship between geographical and seasonal factors and the incidence of APL in the...
A Prospective, Observational Study to Assess Effect of DTT Treatment on ABO Isoagglutinin Titers in O Blood Group Donors
Shweta Ranjan, MBBS, Prashant Pandey, MD, Divya Setya, DNB and Supriya Kumari, MBBS
Article Type: Original Article | First Published: December 08, 2022
To determine actual concentration of clinically significant IgG antibodies, there is need to inactivate IgM antibodies. Aim of this study was to study effect of dithiothreitol (DTT) on ABO isoagglutinin titers performed by column agglutination technology (CAT) and conventional tube technique (CTT) and to compare results obtained by DTT treatment. This was a prospective, observational study conducted from October 2018 to March 2020. All consecutive O group donors were included. All samples were c...
Iliopsoas Hematoma as Unusually Early Onset of Hemophilia A in a Young Infant
Coppo D, Rossi L, Raffaldi I, Aguzzi S, Castagno E, Ricca I and Bondone C
Article Type: Case Report | First Published: November 14, 2022
A 2-month-old infant was admitted for irritability and hypomobility of the left lower limb. Ultrasound revealed a deep hematoma of the iliopsoas muscle and coagulation tests showed increased activated partial thromboplastin time (aPTT). The finding of marked reduction of blood coagulation factor VIII (FVIII) led to the diagnosis of severe Hemophilia A. The infants were promptly put on i.v. factor VIII concentrates, resulting in rapid clinical improvement....
Magnetic Therapy of Anemia Caused by Inflammations
Article Type: Original Article | First Published: October 13, 2022
In my paper I describe the magnetic therapy of anemia caused by inflammations, and I explain the physical processes underlying this therapy. Anemia occurs when there are not enough healthy red blood cells to carry oxygen to the organs of the body. The patients suffering from anemia feel cold, tired and weak. The most common type of anemia is the iron deficiency anemia. Iron produces a substance in the red blood cells then enables them to carry oxygen (hemoglobin)....
Evaluation of Changes in Haemostatic Parameters in Pregnancy and Puerperium in Women attending Antenatal Clinic at Rivers State University Teaching Hospital, Nigeria
Echonwere-Uwikor, B.E, Moore-Igwe, BW, Chukuigwe-Igbere, O.E and Chuku, P.H
Article Type: Original Article | First Published: September 15, 2022
This was a cross-sectional study carried out in Rivers State University Teaching Hospital, Port Harcourt with the aim of determining the Changes in Haemostatic Parameters in Pregnancy and puerperium. A total of 500 age-matched apparently healthy women of reproductive age, which consisted of 200 (40%) pregnant women, 200 (40%) puerperium mothers and 100 (20%) non-pregnant women who served as controls were studied. Their ages ranged from 16 to 41 years (mean 27.4 ± 4.3 years)....
Under Reported Potentials of Low Foetal Haemoglobin Concentration in Sickle Cell Disease
Yusuf Ishaya Dogonzo, Obinna Charles Ekoh and Thankgod Nnanna Enewor
Article Type: Original Article | First Published: August 29, 2022
The liver plays a significant role in the maintenance of health and survival of an individual. Any threat to this important organ is a threat to the existence of life. Hence its protection is vital to survival. Individuals with SCD are at high risk of suffering from liver failure due to events resulting from HbS polymerization....
Hemophagocytic Lymphohistiocytosis in A Post Covid-19 Patient with Mds: A Case Report
Ioannis Vasilopoulos, MD, Marina P Siakantaris, MD, PhD, Kalliope Zerzi, MD, Eliana A Konstantinou, MD, John V Asimakopoulos, MD, PhD, Anestis Karapaschalidis, MD, Fotios Panitsas, MD, MSc, Eleni Plata, MD, Maria K Angelopoulou, MD, Theodoros P Vassilakopoulos, MD, PhD and Panayiotis Tsaftaridis, MD, PhD
Article Type: Case Report | First Published: July 13, 2022
Primary or secondary hemophagocytic lymphohistiocytosis (HLH) is characterized by immune activation and lifethreatening cytopenias. Causative relationship between a number of pathogens, autoimmune diseases and even hematologic malignancies with secondary HLH (sHLH) have been reported....