International Journal of

Clinical Biostatistics and BiometricsISSN: 2469-5831


 Open Access DOI:10.23937/2469-5831/1510049

Hypothyroidism: A Small Clinical Trial Will Quickly Resolve the Combination Therapy Controversy

Timothy A Welborn, AO, PhD, FRCP, FRACP, MBBS and Satvinder S Dhaliwal, PhD, MSc, BSC

Article Type: Letter | First Published: October 23, 2022

Hypothyroidism is an extremely common condition. More than 100 million prescriptions for thyroxine (T4) are processed in the USA each year. T4 is the recommended treatment for hypothyroidism. But 5-15% of patients treated to target with T4 continue to have symptoms. Some of these patients respond dramatically to the addition of triiodothyronine (T3) as first reported 20 years ago....

 Open Access DOI:10.23937/2469-5831/1510048

A New Modified Liu Ridge-Type Estimator for the Linear Regression Model: Simulation and Application

Olasunkanmi J Oladapo, Abiola T Owolabi, Janet I Idowu and Kayode Ayinde

Article Type: Original Research | First Published: July 09, 2022

Several efforts have been made to solve the multicollinearity problem, which arises from correlated regressors in the linear regression model. This is because the Ordinary Least Squares (OLS) Estimator becomes inefficient in the presence of multicollinearity....

 Open Access DOI:10.23937/2469-5831/1510047

Development of a Novel Retrospective Instrument to Gauge the General Well-being Index and Lumbar Specific Disability Index Post Intervention in Lumbar Degenerative Disease

Song Ying Chong, MBBS, Mahmoud Danaee, PhD and Dharmendra Ganesan, FRCS

Article Type: Original Article | First Published: July 04, 2022

The clinical outcome data for patients who had a particular intervention for the lumbar degenerative disease is based on changes in symptomatology. This functional data had been acquired in a prospective manner using standard tools e.g., ODI, RMQ, SF-36 etc. Such data may be lacking in many facilities of developing countries due to various reasons....

Volume 8
Issue 2